Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells. (Q48617628)

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scientific article published on 15 March 2006

Language	Label	Description	Also known as
English	Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells.	scientific article published on 15 March 2006

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scholarly article

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells. (English)

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

author name string

Sondag CM

1

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

Combs CK

2

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

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publication date

15 March 2006

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

Journal of Neurochemistry

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13 February 2018

http://europepmc.org/abstract/MED/16539666

97

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

2

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

449-461

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13 February 2018

http://europepmc.org/abstract/MED/16539666

Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia.

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Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

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In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells

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Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I.

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beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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A cytoplasmic inhibitor of the JNK signal transduction pathway

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

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Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

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Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

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Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.

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Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein

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The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

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Beta-amyloid precursor protein is detectable on monocytes and is increased in Alzheimer's disease

1 reference

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Interaction of Alzheimer beta-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-alpha

1 reference

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Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals.

1 reference

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Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

1 reference

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beta-Amyloid induces increased release of interleukin-1 beta from lipopolysaccharide-activated human monocytes

1 reference

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Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes

1 reference

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Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells

1 reference

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Ligand-dependent G protein coupling function of amyloid transmembrane precursor

1 reference

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A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis

1 reference

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Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

1 reference

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The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

1 reference

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Peripheral cytokine release in Alzheimer patients: correlation with disease severity

1 reference

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Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease.

1 reference

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

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In vivo protein transduction: delivery of a biologically active protein into the mouse

1 reference

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Homo- and heterodimerization of APP family members promotes intercellular adhesion

1 reference

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Amyloid precursor protein mediates proinflammatory activation of monocytic lineage cells

1 reference

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Expression of beta-amyloid precursor protein-CD3gamma chimeras to demonstrate the selective generation of amyloid beta(1-40) and amyloid beta(1-42) peptides within secretory and endocytic compartments

1 reference

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Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

1 reference

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Localization of a fibrillar amyloid beta-protein binding domain on its precursor

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Fibrillar amyloid beta-protein binds protease nexin-2/amyloid beta-protein precursor: stimulation of its inhibition of coagulation factor XIa.

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The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain

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Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia

1 reference

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Intracellular and cell-surface distribution of amyloid precursor protein in cortical astrocytes.

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Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

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Identifiers

10.1111/J.1471-4159.2006.03759.X

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16539666

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