Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (Q24292400)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11877420%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11877420%20AND%20SRC:MED&resulttype=core&format=json

Amyloid beta (A4) precursor protein

7 December 2019

main subject

phosphorylation

0 references

1 reference

Src homology 2 domain-containing transforming protein C3

GOA release 2020-03-11

1 reference

Neurotrophic tyrosine kinase, receptor, type 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Luciano D'Adamio

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11877420%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Luciano D'Adamio

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11877420%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1

Philip E Tarr

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11877420%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

author name string

Roberta Roncarati

2

1 reference

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7 December 2019

Giuliana Pelicci

3

1 reference

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7 December 2019

Pier Giuseppe Pelicci

4

1 reference

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7 December 2019

language of work or name

English

0 references

publication date

4 March 2002

1 reference

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7 December 2019

number of pages

7

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11877420%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

volume

277

1 reference

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7 December 2019

issue

19

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7 December 2019

page(s)

16798-16804

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Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR.

7 December 2019

cites work

1 reference

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7 January 2021

Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain

1 reference

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7 January 2021

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

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7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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7 January 2021

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

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7 January 2021

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

1 reference

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7 January 2021

Elevated expression of p21ras is an early event in Alzheimer's disease and precedes neurofibrillary degeneration

1 reference

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7 January 2021

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

1 reference

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7 January 2021

The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons

1 reference

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7 January 2021

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

1 reference

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7 January 2021

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

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7 January 2021

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

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7 January 2021

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

1 reference

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7 January 2021

The p66shc adaptor protein controls oxidative stress response and life span in mammals

1 reference

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7 January 2021

Shc signaling in differentiating neural progenitor cells.

1 reference

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7 January 2021

Reactivating kinase/p38 phosphorylates tau protein in vitro.

1 reference

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7 January 2021

Phosphorylation Sites on Tau Identified by Nanoelectrospray Mass Spectrometry

1 reference

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7 January 2021

Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.

1 reference

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7 January 2021

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1 reference

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7 January 2021

Shc Binding to Nerve Growth Factor Receptor Is Mediated by the Phosphotyrosine Interaction Domain

1 reference

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7 January 2021

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Ligand-dependent G protein coupling function of amyloid transmembrane precursor

1 reference

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7 January 2021

Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

1 reference

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7 January 2021

Effects of the beta-amyloid and carboxyl-terminal fragment of Alzheimer's amyloid precursor protein on the production of the tumor necrosis factor-alpha and matrix metalloproteinase-9 by human monocytic THP-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

A portrait of Alzheimer secretases--new features and familiar faces

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

1 reference

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7 January 2021

Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

1 reference

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7 January 2021

Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110286200

7 January 2021

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

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7 January 2021

Identifiers

DOI

10.1074/JBC.M110286200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11877420%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference