Direct angiotensin type 2 receptor (AT2R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice (Q48643095)

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scientific article published in January 2015

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English	Direct angiotensin type 2 receptor (AT2R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice	scientific article published in January 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/25052203

Direct angiotensin type 2 receptor (AT2R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice (English)

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/25052203

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experimental autoimmune encephalomyelitis

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Thomas Unger

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13 February 2018

Ulrike Steckelings

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U Muscha Steckelings

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Ludovit Paulis

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Pawel Namsolleck

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Pawel Namsolleck

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Colin Sumners

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Christa Thoene-Reineke

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Christa Thoene-Reineke

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13 February 2018

http://europepmc.org/abstract/MED/25052203

Florianne Monnet-Tschudi

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Florianne Monnet-Tschudi

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13 February 2018

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Anders Hallberg

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Anders Hallberg

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Leon A Danyel

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Verónica Valero-Esquitino

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13 February 2018

http://europepmc.org/abstract/MED/25052203

Kristin Lucht

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http://europepmc.org/abstract/MED/25052203

Tobias Stubbe

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Franziska Lucht

6

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http://europepmc.org/abstract/MED/25052203

Meng Liu

7

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http://europepmc.org/abstract/MED/25052203

Friederike Ebner

8

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http://europepmc.org/abstract/MED/25052203

Christine Brandt

9

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http://europepmc.org/abstract/MED/25052203

Daniel C Villela

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Björn Dahlöf

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13 February 2018

http://europepmc.org/abstract/MED/25052203

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publication date

1 January 2015

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Clinical Science

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http://europepmc.org/abstract/MED/25052203

128

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95-109

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13 February 2018

http://europepmc.org/abstract/MED/25052203

Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination

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CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity

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Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system

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Angiotensin II sustains brain inflammation in mice via TGF-beta

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Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.

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21 January 2018

The angiotensin II AT2 receptor inhibits proliferation and promotes differentiation in PC12W cells

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The angiotensin II type 2 (AT2) receptor promotes axonal regeneration in the optic nerve of adult rats

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Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation

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Angiotensin II type 2 receptor stimulation initiated after stroke causes neuroprotection in conscious rats

1 reference

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21 January 2018

Direct stimulation of angiotensin II type 2 receptor enhances spatial memory

1 reference

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21 January 2018

AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression

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21 January 2018

Protective arms of the renin-angiotensin-system in neurological disease

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21 January 2018

The angiotensin AT2 receptor in inflammation

1 reference

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21 January 2018

Angiotensin AT2 receptor stimulation causes neuroprotection in a conscious rat model of stroke.

1 reference

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21 January 2018

AT1 receptor antagonism is proangiogenic in the brain: BDNF a novel mediator.

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21 January 2018

Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.

1 reference

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21 January 2018

Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?

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21 January 2018

Microglial cell activation and proliferation precedes the onset of CNS autoimmunity

1 reference

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21 January 2018

Inflammatory responses in aggregating rat brain cell cultures subjected to different demyelinating conditions

1 reference

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21 January 2018

Nitric oxide synthase expression and nitric oxide toxicity in oligodendrocytes

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21 January 2018

Promoting myelin repair and return of function in multiple sclerosis

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21 January 2018

Angiotensin II modulates BBB permeability via activation of the AT(1) receptor in brain endothelial cells

1 reference

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21 January 2018

Blockade of AT1 receptors protects the blood-brain barrier and improves cognition in Dahl salt-sensitive hypertensive rats

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21 January 2018

Expression of astrocytic type 2 angiotensin receptor in central nervous system inflammation correlates with blood-brain barrier breakdown

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21 January 2018

Commercially available angiotensin II At₂ receptor antibodies are nonspecific.

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21 January 2018

Role of glial cells in innate immunity and their role in CNS demyelination

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21 January 2018

Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB.

1 reference

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21 January 2018

Regulation of inhibitory protein-kappaB and monocyte chemoattractant protein-1 by angiotensin II type 2 receptor-activated Src homology protein tyrosine phosphatase-1 in fetal vascular smooth muscle cells

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21 January 2018

Microglia: key innate immune cells of the brain

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21 January 2018

The biology of CNS remyelination: the key to therapeutic advances.

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21 January 2018

BDNF: the career of a multifaceted neurotrophin in spinal cord injury

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Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension

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Microbore liquid chromatography with UV detection to study the in vivo passage of compound 21, a non-peptidergic AT₂ receptor agonist, to the striatum in rats

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Blood–brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE

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Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.

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Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

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Identifiers

10.1042/CS20130601

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/25052203

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/25052203

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