Anticonvulsant properties of two GABA uptake inhibitors NNC 05-2045 and NNC 05-2090, not acting preferentially on GAT-1. (Q48666269)

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5 November 2019

title

Anticonvulsant properties of two GABA uptake inhibitors NNC 05-2045 and NNC 05-2090, not acting preferentially on GAT-1 (English)

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5 November 2019

1

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5 November 2019

Anders Fink-Jensen

3

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5 November 2019

author name string

C Thomsen

2

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5 November 2019

J Lundbeck

4

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5 November 2019

B Søkilde

5

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C M Man

6

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P O Sørensen

7

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B Meldrum

8

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5 November 2019

publication date

1 July 1997

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5 November 2019

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5 November 2019

volume

28

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5 November 2019

issue

1

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5 November 2019

page(s)

51-61

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Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Cloning and expression of a betaine/GABA transporter from human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

(R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Functional expression and CNS distribution of a beta-alanine-sensitive neuronal GABA transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

GABA in the inferior colliculus plays a critical role in control of audiogenic seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

GABA in epilepsy: the pharmacologic basis

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Cloning and expression of a rat brain GABA transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Production of specific antibodies against GABA transporter subtypes (GAT1, GAT2, GAT3) and their application to immunocytochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Epilepsy and γ-Aminobutyric Acid-Mediated Inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

GAT-3, a high-affinity GABA plasma membrane transporter, is localized to astrocytic processes, and it is not confined to the vicinity of GABAergic synapses in the cerebral cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Modification of seizure activity by electrical stimulation. II. Motor seizure

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Adjunctive treatment of partial seizures with tiagabine: a placebo-controlled trial.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

Comparison of the anticonvulsant effects of two novel GABA uptake inhibitors and diazepam in amygdaloid kindled rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

The gamma-aminobutyric acid uptake inhibitor, tiagabine, is anticonvulsant in two animal models of reflex epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

A review of the preclinical pharmacology of tiagabine: a potent and selective anticonvulsant GABA uptake inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900033-8

7 January 2021

10.1016/S0920-1211(97)00033-8

Identifiers

DOI

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5 November 2019

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