Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult. (Q48750289)

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27 February 2020

title

Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult (English)

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7

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Kai Uwe Eckardt

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27 February 2020

author name string

Melanie Vogler

1

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Anke Zieseniss

2

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Amke R Hesse

3

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Elif Levent

4

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27 February 2020

Malte Tiburcy

5

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Eva Heinze

6

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27 February 2020

Gunnar Schley

8

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Carsten Willam

10

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Dörthe M Katschinski

11

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publication date

13 January 2015

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27 February 2020

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volume

467

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issue

10

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27 February 2020

page(s)

2141-2149

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Inhibition of prolyl 4-hydroxylase by oxalyl amino acid derivatives in vitro, in isolated microsomes and in embryonic chicken tissues

27 February 2020

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Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.

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Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse

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Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia

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Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy

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Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke

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Age-dependent increase of prolyl-4-hydroxylase domain (PHD) 3 expression in human and mouse heart

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25578858

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25578858

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25578858

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00424-014-1667-Z

1 reference

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27 February 2020

1 reference