Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner. (Q48794853)

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scientific article published in July 2001

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English	Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner.	scientific article published in July 2001

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scholarly article

1 reference

Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner. (English)

1 reference

Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

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author name string

Vincent B

1

1 reference

Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

Smith JD

2

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Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

language of work or name

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publication date

1 July 2001

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Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

European Journal of Neuroscience

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Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

14

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Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

2

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Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

256-266

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Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

1 reference

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Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures.

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.

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Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

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Regulation of amyloid precursor protein cleavage.

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Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

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21 January 2018

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

1 reference

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21 January 2018

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

1 reference

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Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females

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Aggravated decrease in the activity of nucleus basalis neurons in Alzheimer's disease is apolipoprotein E-type dependent

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21 January 2018

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

1 reference

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

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Human apolipoprotein E allele-specific brain expressing transgenic mice.

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

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Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

1 reference

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Distinct pools of synaptic vesicles in neurotransmitter release

1 reference

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LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation

1 reference

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Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

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21 January 2018

Identifiers

10.1046/J.0953-816X.2001.01643.X

1 reference

Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

1 reference

Europe PubMed Central

15 February 2018

http://europepmc.org/abstract/MED/11553277

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