Electrophysiological Analysis of the Mutated Na,K-ATPase Cation Binding Pocket (Q48820652)

15 February 2018

title

Electrophysiological Analysis of the Mutated Na,K-ATPase Cation Binding Pocket (English)

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https://api.crossref.org/works/10.1074/JBC.M306384200

19 March 2024

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https://api.crossref.org/works/10.1074/JBC.M306384200

19 March 2024

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https://api.crossref.org/works/10.1074/JBC.M306384200

19 March 2024

2

Sven Geibel

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Ernst Bamberg

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15 February 2018

author name string

Eva Grabsch

3

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15 February 2018

Thomas Friedrich

6

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15 February 2018

Jan B. Koenderink

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14532287

19 March 2024

Jan Joep H. H M. De Pont

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14532287

19 March 2024

language of work or name

English

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publication date

7 October 2003

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15 February 2018

full work available at URL

number of pages

10

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based on heuristic

inferred from page(s)

http://www.jbc.org/article/S0021925820753792/pdf

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14532287

https://api.elsevier.com/content/article/PII:S0021925820753792?httpAccept=text/xml

19 March 2024

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https://api.crossref.org/works/10.1074/JBC.M306384200

https://api.elsevier.com/content/article/PII:S0021925820753792?httpAccept=text/plain

19 March 2024

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https://api.crossref.org/works/10.1074/JBC.M306384200

https://syndication.highwire.org/content/doi/10.1074/jbc.M306384200

19 March 2024

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https://api.crossref.org/works/10.1074/JBC.M306384200

Journal of Biological Chemistry

19 March 2024

published in

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15 February 2018

volume

278

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15 February 2018

issue

51

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15 February 2018

page(s)

51213-51222

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15 February 2018

Utilization of binding energy and coupling rules for active transport and other coupled vectorial processes.

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Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution

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Voltage dependence of Na translocation by the Na/K pump.

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Access channel model for the voltage dependence of the forward-running Na+/K+ pump

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Characteristics of the Na+/K+-ATPase from Torpedo californica expressed in Xenopus oocytes: a combination of tracer flux measurements with electrophysiological measurements

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Substitution of glutamic 779 with alanine in the Na,K-ATPase alpha subunit removes voltage dependence of ion transport.

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Electrogenic sodium-sodium exchange carried out by Na,K-ATPase containing the amino acid substitution Glu779Ala

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The role of Na,K-ATPase alpha subunit serine 775 and glutamate 779 in determining the extracellular K+ and membrane potential-dependent properties of the Na,K-pump

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The current produced by the E779A mutant rat Na(+)/K(+) pump alpha1-subunit expressed in HEK 293 cells

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Pre-steady-state transient currents mediated by the Na/K pump in internally perfused Xenopus oocytes

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Three distinct and sequential steps in the release of sodium ions by the Na+/K+-ATPase

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A negative slope in the current-voltage relationship of the Na+/K+ pump in Xenopus oocytes produced by reduction of external [K+].

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Electrogenic K+ transport by the Na(+)-K+ pump in rat cardiac ventricular myocytes.

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Role in cation translocation of the N-terminus of the alpha-subunit of the Na(+)-K+ pump of Bufo.

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Significance of the glutamic acid residues Glu334, Glu959, and Glu960 of the alpha subunits of Torpedo Na+, K+ pumps for transport activity and ouabain binding.

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Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry

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Comparison of Na+/K(+)-ATPase pump currents activated by ATP concentration or voltage jumps

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Heteromultimeric CLC chloride channels with novel properties

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High-affinity ouabain binding by a chimeric gastric H+,K+-ATPase containing transmembrane hairpins M3-M4 and M5-M6 of the alpha 1-subunit of rat Na+,K+-ATPase

21 January 2018

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Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Endoplasmic reticulum quality control of oligomeric membrane proteins: topogenic determinants involved in the degradation of the unassembled Na,K-ATPase alpha subunit and in its stabilization by beta subunit assembly

21 January 2018

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Conformational transitions and change translocation by the Na,K pump: comparison of optical and electrical transients elicited by ATP-concentration jumps

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Na+,K(+)-ATPase pump currents in giant excised patches activated by an ATP concentration jump

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Structure-function relationships of cation translocation by Ca(2+)- and Na+, K(+)-ATPases studied by site-directed mutagenesis.

21 January 2018

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Homology modeling of the cation binding sites of Na+K+-ATPase

21 January 2018

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Mutation of aspartate 804 of Na(+),K(+)-ATPase modifies the cation binding pocket and thereby generates a high Na(+)-ATPase activity

21 January 2018

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Asp804 and Asp808 in the transmembrane domain of the Na,K-ATPase alpha subunit are cation coordinating residues

21 January 2018

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Critical effects on catalytic function produced by amino acid substitutions at Asp804 and Asp808 of the alpha1 isoform of Na,K-ATPase

21 January 2018

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A channel mechanism for electrogenic ion pumps

21 January 2018

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Potassium translocation by the Na+/K+ pump is voltage insensitive

21 January 2018

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Mutant Glu781-->Ala of the rat kidney Na+,K(+)-ATPase displays low cation affinity and catalyzes ATP hydrolysis at a high rate in the absence of potassium ions.

21 January 2018

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Substitutions of glutamate 781 in the Na,K-ATPase alpha subunit demonstrate reduced cation selectivity and an increased affinity for ATP.

21 January 2018

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21 January 2018

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The order of release of sodium and addition of potassium in the sodium-potassium pump reaction mechanism

19 March 2024

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Electrogenic sodium pump in nerve and muscle cells

19 March 2024

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Recent electrical snapshots of the cardiac Na,K pump

19 March 2024

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Voltage dependence of Na/K pump current in Xenopus oocytes

19 March 2024

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Channel-like function of the Na,K pump probed at microsecond resolution in giant membrane patches

19 March 2024

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19 March 2024

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A role for the beta-subunit in the expression of functional Na+-K+-ATPase in Xenopus oocytes

19 March 2024

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Importance of intramembrane carboxylic acids for occlusion of K+ ions at equilibrium in renal Na,K-ATPase

19 March 2024

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Identification of Asp804 and Asp808 as Na+ and K+ coordinating residues in alpha-subunit of renal Na,K-ATPase

19 March 2024

48

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Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase

19 March 2024

49

1 reference

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Functional role of oxygen-containing residues in the fifth transmembrane segment of the Na,K-ATPase alpha subunit

19 March 2024

53

1 reference

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19 March 2024

Identifiers

1 reference

15 February 2018

1 reference

15 February 2018