Selection of non-competitive leptin antagonists using a random nanobody-based approach. (Q48944298)

17 February 2018

title

Selection of non-competitive leptin antagonists using a random nanobody-based approach. (English)

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17 February 2018

author name string

Lennart Zabeau

1

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17 February 2018

Annick Verhee

2

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17 February 2018

Dominiek Catteeuw

3

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17 February 2018

Liesbeth Faes

4

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17 February 2018

Sylvie Seeuws

5

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17 February 2018

Tine Decruy

6

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17 February 2018

Dirk Elewaut

7

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17 February 2018

Frank Peelman

8

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17 February 2018

Jan Tavernier

9

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17 February 2018

language of work or name

English

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publication date

1 January 2012

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17 February 2018

number of pages

10

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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17 February 2018

volume

441

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17 February 2018

issue

1

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17 February 2018

page(s)

425-434

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17 February 2018

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

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Identification of targets of leptin action in rat hypothalamus

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The role of neuropeptide Y in the antiobesity action of the obese gene product

21 January 2018

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21 January 2018

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Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby Canine Kidney cells

21 January 2018

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Competitive inhibition of leptin signaling results in amelioration of liver fibrosis through modulation of stellate cell function.

21 January 2018

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Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer

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21 January 2018

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21 January 2018

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Induction of immune responses and molecular cloning of the heavy chain antibody repertoire of Lama glama

21 January 2018

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Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis.

21 January 2018

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Generation of a Phenotypic Array of Hypothalamic Neuronal Cell Models to Study Complex Neuroendocrine Disorders

21 January 2018

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Leptin receptor activation depends on critical cysteine residues in its fibronectin type III subdomains

21 January 2018

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Mapping of binding site III in the leptin receptor and modeling of a hexameric leptin.leptin receptor complex

21 January 2018

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Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

21 January 2018

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Isolation of antigen specific llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae

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Functional Analysis of Leptin Receptor Activation Using a Janus Kinase/Signal Transducer and Activator of Transcription Complementation Assay

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A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

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Mapping of the interface between leptin and the leptin receptor CRH2 domain.

21 January 2018

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Mapping leptin-interacting sites in recombinant leptin-binding domain (LBD) subcloned from chicken leptin receptor

21 January 2018

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Identification of the hydrophobic strand in the A-B loop of leptin as major binding site III: implications for large-scale preparation of potent recombinant human and ovine leptin antagonists.

21 January 2018

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Mapping of the leptin binding sites and design of a leptin antagonist

21 January 2018

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Activation of the Leptin Receptor by a Ligand-induced Conformational Change of Constitutive Receptor Dimers

21 January 2018

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Development of leptin antagonists and their potential use in experimental biology and medicine

21 January 2018

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

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21 January 2018

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21 January 2018

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Astrocytes in the arcuate nucleus and median eminence that take up a fluorescent dye from the circulation express leptin receptors and neuropeptide Y Y1 receptors

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20110438

1 reference

17 February 2018

PubMed ID

21851341

1 reference

17 February 2018