Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased. (Q49115733)

18 February 2018

title

Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased. (English)

1 reference

18 February 2018

author name string

Xie C

1

1 reference

18 February 2018

Burns DK

2

1 reference

18 February 2018

Turley SD

3

1 reference

18 February 2018

Dietschy JM

4

1 reference

18 February 2018

publication date

1 December 2000

1 reference

18 February 2018

Journal of Neuropathology & Experimental Neurology

published in

1 reference

18 February 2018

volume

59

1 reference

18 February 2018

page(s)

1106-1117

1 reference

18 February 2018

issue

12

1 reference

18 February 2018

Cerebellar degeneration in the Niemann-Pick type C mouse.

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Nova Scotia Niemann-Pick disease (type D): clinical study of 20 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Niemann-Pick disease type C

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Lipid changes in Niemann-Pick disease type C brain: personal experience and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Recycling receptors: The round-trip itinerary of migrant membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Kinetic parameters for high density lipoprotein apoprotein AI and cholesteryl ester transport in the hamster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Sterol synthesis and low density lipoprotein clearance in vivo in the pregnant rat, placenta, and fetus. Sources for tissue cholesterol during fetal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Nerve injury stimulates the secretion of apolipoprotein E by nonneuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

The measurement of the exchangeable pools of cholesterol in the baboon

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Nerve regeneration occurs in the absence of apolipoprotein E in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

Embryonic Striatal Neurons from Niemann-Pick Type C Mice Exhibit Defects in Cholesterol Metabolism and Neurotrophin Responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F59.12.1106

21 January 2018

Identifiers

DOI

10.1093/JNEN/59.12.1106

1 reference

18 February 2018

PubMed ID

11138930

1 reference

18 February 2018