Roles of neutrophils in cancer growth and progression. (Q49973375)

23 February 2018

title

Roles of neutrophils in cancer growth and progression. (English)

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23 February 2018

4

Alberto Mantovani

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23 February 2018

2

Gilda Varricchi

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23 February 2018

author name string

Maria Rosaria Galdiero

series ordinal

1

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23 February 2018

Stefania Loffredo

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3

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23 February 2018

Gianni Marone

series ordinal

5

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23 February 2018

publication date

15 December 2017

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23 February 2018

Journal of Leukocyte Biology

published in

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23 February 2018

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

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Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

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Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth

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Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells

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Breast cancer cell uptake of the inflammatory mediator neutrophil elastase triggers an anticancer adaptive immune response

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Breast cancer cells stimulate neutrophils to produce oncostatin M: potential implications for tumor progression

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Neutrophils enhance invasion activity of human cholangiocellular carcinoma and hepatocellular carcinoma cells: an in vitro study

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Mismatch repair deficient colorectal cancer in the era of personalized treatment

21 January 2018

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Neutrophil stimulation with Mycobacterium bovis bacillus Calmette-Guerin (BCG) results in the release of functional soluble TRAIL/Apo-2L

21 January 2018

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Treatment with IFNalpha in vivo up-regulates serum-soluble TNF-related apoptosis inducing ligand (sTRAIL) levels and TRAIL mRNA expressions in neutrophils in chronic myelogenous leukemia patients.

21 January 2018

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IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells

21 January 2018

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Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

21 January 2018

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Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells

21 January 2018

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γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer.

21 January 2018

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A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer

21 January 2018

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Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis

21 January 2018

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Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis

21 January 2018

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Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer

21 January 2018

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Bv8 regulates myeloid-cell-dependent tumour angiogenesis

21 January 2018

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Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression

21 January 2018

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G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models

21 January 2018

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Angiogenic activity of bFGF and VEGF suppressed by proteolytic cleavage by neutrophil elastase

21 January 2018

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CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A.

21 January 2018

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Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils.

21 January 2018

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Transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development

21 January 2018

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Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

21 January 2018

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Tumor entrained neutrophils inhibit seeding in the premetastatic lung

21 January 2018

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Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade

21 January 2018

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A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs

21 January 2018

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Characterization of a novel population of low-density granulocytes associated with disease severity in HIV-1 infection

21 January 2018

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Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes

21 January 2018

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The diversity of circulating neutrophils in cancer

21 January 2018

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21 January 2018

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Myeloid-derived suppressor cells as regulators of the immune system

21 January 2018

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TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients

21 January 2018

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Neutrophil degranulation and immunosuppression in patients with GBM: restoration of cellular immune function by targeting arginase I.

21 January 2018

1 reference

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Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

21 January 2018

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Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils

21 January 2018

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Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer.

21 January 2018

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Immunomonitoring and prognostic relevance of neutrophils in clinical trials.

21 January 2018

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Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma

21 January 2018

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Increased intratumoral neutrophil in colorectal carcinomas correlates closely with malignant phenotype and predicts patients' adverse prognosis

21 January 2018

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Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease

21 January 2018

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The significance of tumor-associated neutrophil density in uterine cervical cancer treated with definitive radiotherapy.

21 January 2018

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Neutrophil infiltration into human gliomas

21 January 2018

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Tumor-infiltrating neutrophils in pancreatic neoplasia

21 January 2018

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The prognostic landscape of genes and infiltrating immune cells across human cancers

21 January 2018

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Neutrophils dominate the immune cell composition in non-small cell lung cancer

21 January 2018

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Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer

21 January 2018

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High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor.

21 January 2018

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Elevated preoperative neutrophil-to-lymphocytes ratio predicts poor prognosis after esophagectomy in T1 esophageal cancer.

21 January 2018

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Role of neutrophil-to-lymphocyte ratio in prediction of Gleason score upgrading and disease upstaging in low-risk prostate cancer patients eligible for active surveillance

21 January 2018

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Performance status and neutrophil-lymphocyte ratio are important prognostic factors in elderly patients with unresectable pancreatic cancer

21 January 2018

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Prognostic role of neutrophil-to-lymphocyte ratio in breast cancer: a systematic review and meta-analysis

21 January 2018

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The systemic inflammation-based neutrophil-lymphocyte ratio: experience in patients with cancer

21 January 2018

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Immune mediators as potential diagnostic tools for colorectal cancer: from experimental rationale to early clinical evidence

21 January 2018

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Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

21 January 2018

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The secret ally: immunostimulation by anticancer drugs

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The future of immune checkpoint therapy

21 January 2018

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Immune suppression by neutrophils in HIV-1 infection: role of PD-L1/PD-1 pathway

21 January 2018

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Up-regulation of programmed cell death 1 ligand 1 on neutrophils may be involved in sepsis-induced immunosuppression: an animal study and a prospective case-control study.

21 January 2018

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Programmed death ligand 1 on Burkholderia pseudomallei-infected human polymorphonuclear neutrophils impairs T cell functions

21 January 2018

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Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis

21 January 2018

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PD-L1-expressing neutrophils as a novel indicator to assess disease activity and severity of systemic lupus erythematosus

21 January 2018

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Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway

21 January 2018

1 reference

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Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation

21 January 2018

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CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

21 January 2018

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Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil

21 January 2018

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Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JLB.3MR0717-292R

1 reference

23 February 2018

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23 February 2018