Mismatch repair deficient colorectal cancer in the era of personalized treatment (Q37696965)

22 August 2017

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title

Mismatch repair deficient colorectal cancer in the era of personalized treatment (English)

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22 August 2017

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2

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22 August 2017

David Cunningham

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Alan Ashworth

series ordinal

5

object named as

Alan Ashworth

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22 August 2017

1

Madeleine Hewish

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22 August 2017

Sarah A Martin

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PubMed ID

20177404

22 August 2017

language of work or name

English

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publication date

23 February 2010

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Nature Reviews Clinical Oncology

22 August 2017

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22 August 2017

7

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22 August 2017

197-208

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22 August 2017

4

1 reference

Histopathological identification of colon cancer with microsatellite instability

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin.

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1 reference

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Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability.

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1 reference

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A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer

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Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg?

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1 reference

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Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part I. The utility of immunohistochemistry

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Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part II. The utility of microsatellite instability testing

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1 reference

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Differences and evolution of the methods for the assessment of microsatellite instability

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https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

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The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside

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1 reference

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Prediction of germline mutations and cancer risk in the Lynch syndrome

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1 reference

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Prediction of MLH1 and MSH2 Mutations in Lynch Syndrome

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1 reference

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Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer

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Identification in Daily Practice of Patients With Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer): Revised Bethesda Guidelines-Based ApproachVersusMolecular Screening

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1 reference

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Guidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers syndrome

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Quality of life after total colectomy with ileorectal anastomosis or proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis.

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Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer

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Deficient mismatch repair system in patients with sporadic advanced colorectal cancer

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Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial

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The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status.

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CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

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Moyamoya disease and moyamoya syndrome

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Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer.

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Chromosomal instability in microsatellite-unstable and stable colon cancer

31 March 2020

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Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis

31 March 2020

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Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients

31 March 2020

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Chemotherapy for colorectal cancer

31 March 2020

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31 March 2020

Capecitabine: a review

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DNA mismatch repair-dependent response to fluoropyrimidine-generated damage.

31 March 2020

1 reference

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Metabolism and mechanism of action of 5-fluorouracil

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Mismatch repair proficiency and in vitro response to 5-fluorouracil

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Differential growth inhibition by 5-fluorouracil in human colorectal carcinoma cell lines.

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Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.

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1 reference

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The mismatch repair complex hMutS alpha recognizes 5-fluorouracil-modified DNA: implications for chemosensitivity and resistance

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1 reference

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Levamisole: known effects on the immune system, clinical results, and future applications to the treatment of cancer

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Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations.

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New approaches to assessing and treating early-stage colon and rectal cancers: cooperative group strategies for assessing optimal approaches in early-stage disease

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1 reference

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Microsatellite instability: a predictive marker in metastatic colorectal cancer?

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Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis

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Thymidylate synthase expression in colon carcinomas with microsatellite instability

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Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance

31 March 2020

1 reference

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Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy.

31 March 2020

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Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample

31 March 2020

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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

31 March 2020

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Oxaliplatin-based chemotherapy in the management of colorectal cancer

31 March 2020

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Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line

31 March 2020

1 reference

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DNA topoisomerases: structure, function, and mechanism

31 March 2020

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Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.

31 March 2020

1 reference

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Resistance to topoisomerase poisons due to loss of DNA mismatch repair

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Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors

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Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells

31 March 2020

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Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines

31 March 2020

1 reference

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Topoisomerase I inhibitors: camptothecins and beyond

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1 reference

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Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.

31 March 2020

1 reference

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Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.

31 March 2020

1 reference

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Sensitivity to DNA cross-linking chemotherapeutic agents in mismatch repair-defective cells in vitro and in xenografts

31 March 2020

1 reference

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Capecitabine and mitomycin C as third-line therapy for patients with metastatic colorectal cancer resistant to fluorouracil and irinotecan

31 March 2020

1 reference

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KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.

31 March 2020

1 reference

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RAF/RAS oncogenes and mismatch-repair status

31 March 2020

1 reference

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Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability

31 March 2020

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ATM is required for the cellular response to thymidine induced replication fork stress.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers

31 March 2020

1 reference

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Targeted therapy for cancer using PARP inhibitors

31 March 2020

1 reference

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Microsatellite instability is frequently observed in rectal cancer and influenced by neoadjuvant chemoradiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

The concept of synthetic lethality in the context of anticancer therapy

31 March 2020

1 reference

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A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

31 March 2020

1 reference

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2

31 March 2020

1 reference

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Phase II trial of docetaxel (Taxotere) in metastatic colorectal carcinoma

31 March 2020

1 reference

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Molecular classification of solid tumours: towards pathway-driven therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Drug resistance reversal--are we getting closer?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

BRAF mutation predicts sensitivity to MEK inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Specific clinical and biological features characterize inflammatory bowel disease associated colorectal cancers showing microsatellite instability.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Mechanisms and functions of DNA mismatch repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Patterns ofPIK3CA alterations in familial colorectal and endometrial carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Mechanisms of tolerance to DNA damaging therapeutic drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Evaluation of novel histone deacetylase inhibitors as therapeutic agents for colorectal adenocarcinomas compared to established regimens with the histoculture drug response assay

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2010.18

Phase I trial of 5-fluorouracil and dipyridamole administered by seventy-two-hour concurrent continuous infusion

31 March 2020

1 reference

12 December 2020

Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway

1 reference

12 December 2020

Response to 5-fluorouracil of orthotopically xenografted human colon cancers with a microsatellite instability: influence of P53 status

1 reference

12 December 2020

The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells.

1 reference

12 December 2020

Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability

1 reference

12 December 2020

Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway.

1 reference

12 December 2020

In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair

1 reference

12 December 2020

Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.

1 reference

12 December 2020

Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells

1 reference

12 December 2020

Characterization of sporadic colon cancer by patterns of genomic instability.

1 reference

12 December 2020

Thymidylate synthase gene promoter polymorphisms are associated with TSmRNA expressions but not with microsatellite instability in colorectal cancer.

1 reference

12 December 2020

Immunological treatment of rheumatoid arthritis

1 reference

12 December 2020

Selective radiosensitization of drug-resistant MutS homologue-2 (MSH2) mismatch repair-deficient cells by halogenated thymidine (dThd) analogues: Msh2 mediates dThd analogue DNA levels and the differential cytotoxicity and cell cycle effects of the

1 reference

12 December 2020

Mucinous colon carcinomas with microsatellite instability have a lower microvessel density and lower vascular endothelial growth factor expression.

1 reference

12 December 2020

Genetic classification of colorectal cancer based on chromosomal loss and microsatellite instability predicts survival

1 reference

12 December 2020

CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer

1 reference

12 December 2020

N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells.

1 reference

12 December 2020

The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression

1 reference

12 December 2020

Microsatellite status and cell cycle associated markers in rectal cancer patients undergoing a combined regimen of 5-FU and CPT-11 chemotherapy and radiotherapy.

1 reference

12 December 2020

Loss of DNA mismatch repair in acquired resistance to cisplatin

1 reference

12 December 2020

Schedule-dependent enhancement of the cytotoxicity of fluoropyrimidines to human carcinoma cells in the presence of folinic acid

1 reference

12 December 2020

The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences

1 reference

12 December 2020

Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer

1 reference

12 December 2020

BRAFMutation in Metastatic Colorectal Cancer

1 reference

12 December 2020

10.1038/NRCLINONC.2010.18

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20177404