Modulators of innate immunity as novel therapeutics for treatment of chronic hepatitis B. (Q49997050)

23 February 2018

title

Modulators of innate immunity as novel therapeutics for treatment of chronic hepatitis B. (English)

1 reference

23 February 2018

3

Stephan Menne

1 reference

23 February 2018

author name string

Aleksei Suslov

series ordinal

1

1 reference

23 February 2018

Stefan Wieland

series ordinal

2

1 reference

23 February 2018

publication date

11 February 2018

1 reference

23 February 2018

Current opinion in virology

published in

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23 February 2018

volume

30

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23 February 2018

page(s)

9-17

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23 February 2018

Hepatitis B Virus Does Not Interfere with Innate Immune Responses in the Human Liver.

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Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B

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Kupffer Cells Support Hepatitis B Virus-Mediated CD8+ T Cell Exhaustion via Hepatitis B Core Antigen-TLR2 Interactions in Mice

8 September 2018

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Immune-modulators to combat hepatitis B virus infection: From IFN-α to novel investigational immunotherapeutic strategies

8 September 2018

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Early inhibition of hepatocyte innate responses by hepatitis B virus.

8 September 2018

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Interferon-λ: Immune Functions at Barrier Surfaces and Beyond

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The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion

8 September 2018

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Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities

8 September 2018

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Trained immunity in newborn infants of HBV-infected mothers

8 September 2018

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Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection

8 September 2018

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Natural Killer Cell Characteristics in Patients With Chronic Hepatitis B Virus (HBV) Infection Are Associated With HBV Surface Antigen Clearance After Combination Treatment With Pegylated Interferon Alfa-2a and Adefovir

8 September 2018

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The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection

8 September 2018

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Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B

8 September 2018

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The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus

8 September 2018

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STING agonists induce an innate antiviral immune response against hepatitis B virus

8 September 2018

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Dissecting the dendritic cell controversy in chronic hepatitis B virus infection

8 September 2018

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Identification of Toll-like receptor 9 as parapoxvirus ovis-sensing receptor in plasmacytoid dendritic cells

8 September 2018

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Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections

8 September 2018

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Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver

8 September 2018

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Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages

8 September 2018

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Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

8 September 2018

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Interferon-stimulated genes: a complex web of host defenses

8 September 2018

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Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver

8 September 2018

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Hepatic immune regulation and its involvement in viral hepatitis infection.

8 September 2018

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Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration.

8 September 2018

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Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes

8 September 2018

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Reduction of HBV replication prolongs the early immunological response to IFNα therapy

8 September 2018

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Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B.

8 September 2018

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Cytosolic sensing of viruses

8 September 2018

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Management of hepatitis B: our practice and how it relates to the guidelines

8 September 2018

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The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells

8 September 2018

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GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees

8 September 2018

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Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion.

8 September 2018

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8 September 2018

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8 September 2018

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Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B.

8 September 2018

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Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B.

8 September 2018

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Transcriptomic analysis of the woodchuck model of chronic hepatitis B

8 September 2018

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8 September 2018

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Peginterferon-α does not improve early peripheral blood HBV-specific T-cell responses in HBeAg-negative chronic hepatitis

8 September 2018

1 reference

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IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome

8 September 2018

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Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA.

8 September 2018

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Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

8 September 2018

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8 September 2018

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Innate immunity to intracellular pathogens: macrophage receptors and responses to microbial entry

8 September 2018

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Hypercytolytic activity of hepatic natural killer cells correlates with liver injury in chronic hepatitis B patients

8 September 2018

1 reference

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Hepatitis B virus lacks immune activating capacity, but actively inhibits plasmacytoid dendritic cell function

8 September 2018

1 reference

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Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection

8 September 2018

1 reference

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Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline

8 September 2018

1 reference

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Pathogenesis of hepatitis E virus and hepatitis C virus in chimpanzees: similarities and differences

8 September 2018

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Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection

8 September 2018

1 reference

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Control of hepatitis B virus replication by innate response of HepaRG cells.

8 September 2018

1 reference

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Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.

8 September 2018

1 reference

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Temporal analysis of early immune responses in patients with acute hepatitis B virus infection

8 September 2018

1 reference

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Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections

8 September 2018

1 reference

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Early kinetics of innate and adaptive immune responses during hepatitis B virus infection

8 September 2018

1 reference

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Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

8 September 2018

1 reference

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Viral evasion and subversion of pattern-recognition receptor signalling

8 September 2018

1 reference

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Evolutionary struggles between NK cells and viruses

8 September 2018

1 reference

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Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation

8 September 2018

1 reference

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Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein

8 September 2018

1 reference

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Stealth and cunning: hepatitis B and hepatitis C viruses

8 September 2018

1 reference

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Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids

8 September 2018

1 reference

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Toll-like receptor signaling inhibits hepatitis B virus replication in vivo.

8 September 2018

1 reference

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Genomic analysis of the host response to hepatitis B virus infection

8 September 2018

1 reference

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Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

8 September 2018

1 reference

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Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice.

8 September 2018

1 reference

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Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice

8 September 2018

1 reference

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Interleukin-12 inhibits hepatitis B virus replication in transgenic mice

8 September 2018

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Prevention of perinatally transmitted hepatitis B virus infections with hepatitis B immune globulin and hepatitis B vaccine

8 September 2018

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Modification of chronic hepatitis-B virus infection in chimpanzees by administration of an interferon inducer

8 September 2018

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Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

8 September 2018

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A phase I/II study of recombinant human interleukin-12 in patients with chronic hepatitis B

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12 December 2020

Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients

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12 December 2020

Demonstration of safety and enhanced seroprotection against hepatitis B with investigational HBsAg-1018 ISS vaccine compared to a licensed hepatitis B vaccine

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12 December 2020

Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues

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12 December 2020

Altered functions of plasmacytoid dendritic cells and reduced cytolytic activity of natural killer cells in patients with chronic HBV infection

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12 December 2020

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Identifiers

DOI

1 reference

23 February 2018

0 references

1 reference

23 February 2018