Reciprocal Regulation of Glycolysis-Driven Th17 Pathogenicity and Regulatory T Cell Stability by Cdc42. (Q50026803)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29440353%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

title

Reciprocal Regulation of Glycolysis-Driven Th17 Pathogenicity and Regulatory T Cell Stability by Cdc42 (English)

1 reference

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16 March 2020

1

1 reference

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16 March 2020

Jun-Qi Yang

2

1 reference

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16 March 2020

author name string

Yuan Li

3

1 reference

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16 March 2020

Yan Meng

4

1 reference

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16 March 2020

Yi Zheng

5

1 reference

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16 March 2020

Fukun Guo

6

1 reference

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16 March 2020

language of work or name

English

0 references

publication date

12 February 2018

1 reference

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16 March 2020

published in

Journal of Immunology

1 reference

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16 March 2020

volume

200

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16 March 2020

issue

7

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16 March 2020

page(s)

2313-2326

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Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability.

16 March 2020

cites work

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Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity

5 October 2018

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TCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of Differentiation

5 October 2018

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Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

5 October 2018

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CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

5 October 2018

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Helios Controls a Limited Subset of Regulatory T Cell Functions

5 October 2018

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The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation

5 October 2018

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Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells

5 October 2018

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Ubiquitin-dependent regulation of Foxp3 and Treg function

5 October 2018

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Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis

5 October 2018

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5 October 2018

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Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease

5 October 2018

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IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance

5 October 2018

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Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

5 October 2018

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Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability

5 October 2018

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Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

5 October 2018

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De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

5 October 2018

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Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus

5 October 2018

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Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis

5 October 2018

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Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells

5 October 2018

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5 October 2018

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Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

5 October 2018

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Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response

5 October 2018

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T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation

5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

5 October 2018

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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

5 October 2018

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The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

5 October 2018

1 reference

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CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

5 October 2018

1 reference

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Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

5 October 2018

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Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis

5 October 2018

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Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

5 October 2018

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

5 October 2018

1 reference

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Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization

5 October 2018

1 reference

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Rho GTPases in cell biology

5 October 2018

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The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis.

5 October 2018

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Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

5 October 2018

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Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways

5 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29440353

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29440353

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1601765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29440353%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29440353%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

PubMed publication ID

29440353

1 reference