Delayed myelination in a mouse model of fragile X syndrome. (Q50313070)

2 March 2018

title

Delayed myelination in a mouse model of fragile X syndrome. (English)

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2 March 2018

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Laura K K Pacey

1

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2 March 2018

Ingrid C Y Xuan

2

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2 March 2018

Sihui Guan

3

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2 March 2018

Dafna Sussman

4

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2 March 2018

R Mark Henkelman

5

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Yan Chen

6

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Christian Thomsen

7

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David R Hampson

8

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2 March 2018

publication date

4 June 2013

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2 March 2018

published in

Human Molecular Genetics

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2 March 2018

volume

22

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2 March 2018

issue

19

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2 March 2018

page(s)

3920-3930

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2 March 2018

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

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Pathways to drug development for autism spectrum disorders

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Decreased cerebellar posterior vermis size in fragile X syndrome: correlation with neurocognitive performance

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Region-specific alterations in brain development in one- to three-year-old boys with fragile X syndrome

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Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome

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Specificity of cerebellar vermian abnormalities in autism: a quantitative magnetic resonance imaging study

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Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k.

21 January 2018

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Bridging the gap between MRI and postmortem research in autism

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Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging

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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

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Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex.

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Developmental expression of FMRP in the astrocyte lineage: implications for fragile X syndrome.

21 January 2018

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Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse

21 January 2018

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Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors

21 January 2018

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Fragile X Protein is required for inhibition of insulin signaling and regulates glial-dependent neuroblast reactivation in the developing brain

21 January 2018

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Early white-matter abnormalities of the ventral frontostriatal pathway in fragile X syndrome

21 January 2018

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Pervasive microstructural abnormalities in autism: a DTI study

21 January 2018

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Fragile x mental retardation (Fmr-1) gene expression is down regulated in brain of mice during aging

21 January 2018

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The diffusion tensor imaging toolbox

21 January 2018

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Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin

21 January 2018

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NG2-expressing cells as oligodendrocyte progenitors in the normal and demyelinated adult central nervous system

21 January 2018

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The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination

21 January 2018

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The NG2 proteoglycan: past insights and future prospects

21 January 2018

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Fragile X and autism: Intertwined at the molecular level leading to targeted treatments

21 January 2018

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The geometric and spatial constraints of the microenvironment induce oligodendrocyte differentiation

21 January 2018

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Neuron-glia communication in the control of oligodendrocyte function and myelin biogenesis

21 January 2018

1 reference

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Axo-glial septate junctions. The maestro of nodal formation and myelination?

21 January 2018

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Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice

21 January 2018

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Oligodendroglial metabotropic glutamate receptors are developmentally regulated and involved in the prevention of apoptosis.

21 January 2018

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Developing oligodendrocytes express functional GABA(B) receptors that stimulate cell proliferation and migration

21 January 2018

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Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures

21 January 2018

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Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.

21 January 2018

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Myelin management by the 18.5-kDa and 21.5-kDa classic myelin basic protein isoforms

21 January 2018

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Distinct molecular mechanisms lead to diminished myelin basic protein and 2',3'-cyclic nucleotide 3'-phosphodiesterase in qk(v) dysmyelination

21 January 2018

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Post-transcriptional regulation of myelin formation.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

FMRP targets distinct mRNA sequence elements to regulate protein expression

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

Regulation of Oligodendrocyte Differentiation and Myelination

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.

21 January 2018

1 reference

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Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile X syndrome

21 January 2018

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Glutamate induces the elongation of early dendritic protrusions via mGluRs in wild type mice, but not in fragile X mice

21 January 2018

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Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

Maternal immune activation in mice delays myelination and axonal development in the hippocampus of the offspring

21 January 2018

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Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism

21 January 2018

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Sex effects on neurodevelopmental outcomes of innate immune activation during prenatal and neonatal life

21 January 2018

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Early musical training and white-matter plasticity in the corpus callosum: evidence for a sensitive period.

21 January 2018

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A critical period for social experience-dependent oligodendrocyte maturation and myelination

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

Prolonged myelination in human neocortical evolution

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

Early developmental alterations in GABAergic protein expression in fragile X knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

Target size regulates calibre and myelination of sympathetic axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT246

21 January 2018

Identifiers

DOI

10.1093/HMG/DDT246

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2 March 2018

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2 March 2018