The pan-caspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis. (Q50473358)

14 March 2018

title

The pan-caspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis. (English)

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non-alcoholic steatohepatitis

main subject

steatohepatitis

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5

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Gregory J Gores

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object named as

Gregory J Gores

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author name string

Fernando J Barreyro

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Silvia Holod

2

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Paola V Finocchietto

3

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Alejandra M Camino

4

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Alejandra Avagnina

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María C Carreras

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Juan J Poderoso

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publication date

6 June 2014

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published in

Liver International

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volume

35

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page(s)

953-966

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issue

3

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Nonalcoholic fatty liver disease

cites work

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Breaking the mitochondrial barrier

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The Caspase Inhibitor IDN-6556 Attenuates Hepatic Injury and Fibrosis in the Bile Duct Ligated Mouse

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First-in-class pan caspase inhibitor developed for the treatment of liver disease

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Identifiers

DOI

10.1111/LIV.12570

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14 March 2018

PubMed ID

24750664

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14 March 2018