Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver (Q44125748)

30 November 2017

Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver (English)

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30 November 2017

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8

Michael P Manns

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30 November 2017

Xandra Volkmann

1

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30 November 2017

Ute Fischer

2

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30 November 2017

Matthias J Bahr

3

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30 November 2017

Michael Ott

4

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30 November 2017

Frank Lehner

5

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30 November 2017

Marion Macfarlane

6

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30 November 2017

Gerald M Cohen

7

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30 November 2017

Klaus Schulze-Osthoff

9

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30 November 2017

Heike Bantel

10

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30 November 2017

language of work or name

English

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publication date

1 November 2007

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30 November 2017

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30 November 2017

46

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30 November 2017

1498-1508

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30 November 2017

5

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Apo2L/TRAIL and its death and decoy receptors

30 November 2017

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7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

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7 January 2021

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

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7 January 2021

TRAIL-R as a negative regulator of innate immune cell responses.

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7 January 2021

Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL.

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7 January 2021

Nature's TRAIL--on a path to cancer immunotherapy

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7 January 2021

Potential and caveats of TRAIL in cancer therapy

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7 January 2021

Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1.

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7 January 2021

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

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7 January 2021

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

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7 January 2021

HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.

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7 January 2021

Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies.

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7 January 2021

Inhibition of Histone Deacetylase Class I but not Class II Is Critical for the Sensitization of Leukemic Cells to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis

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7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

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7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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7 January 2021

Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

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7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

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7 January 2021

Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs.

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7 January 2021

Is TRAIL hepatotoxic?

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7 January 2021

Histological grading and staging of chronic hepatitis

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7 January 2021

The applicability of rat and human liver slices to the study of mechanisms of hepatic drug uptake.

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7 January 2021

Precision-cut liver slices: characteristics and use for in vitro pharmaco-toxicology

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7 January 2021

Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration.

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7 January 2021

A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL

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7 January 2021

Caspase activation is required for antiviral treatment response in chronic hepatitis C virus infection

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7 January 2021

The extent of liver steatosis in chronic hepatitis C virus infection is mirrored by caspase activity in serum

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7 January 2021

Tissue distribution, stability, and pharmacokinetics of Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in human colon carcinoma COLO205 tumor-bearing nude mice

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7 January 2021

Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.

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7 January 2021

Isolated hepatocytes--past, present and future

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7 January 2021

New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures

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7 January 2021

Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors

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7 January 2021

Death receptor-mediated apoptosis and the liver

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7 January 2021

Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury

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7 January 2021

Anticancer activities of histone deacetylase inhibitors

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7 January 2021

Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2

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7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells

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7 January 2021

Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells

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7 January 2021

TRAIL induces apoptosis and inflammatory gene expression in human endothelial cells

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7 January 2021

Regulation of hepatocyte cell cycle progression and differentiation by type I collagen structure

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7 January 2021

In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease

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7 January 2021

Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake

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7 January 2021

Critical roles of TRAIL in hepatic cell death and hepatic inflammation.

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7 January 2021

TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.

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7 January 2021

Dysregulation of apoptosis as a mechanism of liver disease: an overview.

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7 January 2021

Liver cell apoptosis in chronic hepatitis C correlates with histological but not biochemical activity or serum HCV-RNA levels

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7 January 2021

Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection

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7 January 2021

Apoptosis in hepatitis C virus infection

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7 January 2021

Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity

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7 January 2021

Identifiers

DOI

10.1002/HEP.21846

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30 November 2017

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