Microglial VEGF receptor response is an integral chemotactic component in Alzheimer's disease pathology. (Q50607022)

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19 January 2020

title

Microglial VEGF receptor response is an integral chemotactic component in Alzheimer's disease pathology (English)

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19 January 2020

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4

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19 January 2020

author name string

Jae K Ryu

1

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19 January 2020

Taesup Cho

2

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19 January 2020

Hyun B Choi

3

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19 January 2020

James G McLarnon

5

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19 January 2020

language of work or name

English

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publication date

1 January 2009

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19 January 2020

published in

Journal of Neuroscience

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19 January 2020

volume

29

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19 January 2020

issue

1

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19 January 2020

page(s)

3-13

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beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

19 January 2020

cites work

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Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia

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Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells

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Alzheimer's disease and angiogenesis

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Blockade of Vascular Endothelial Growth Factor Receptor I (VEGF-RI), but not VEGF-RII, Suppresses Joint Destruction in the K/BxN Model of Rheumatoid Arthritis

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Expression and Function of the Vascular Endothelial Growth Factor Receptor FLT-1 in Human Eosinophils

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Migration and differentiation of neural precursor cells can be directed by microglia

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12 December 2020

Angiogenic signaling in Alzheimer's disease

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12 December 2020

Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease

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NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.

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12 December 2020

VEGF and VEGF receptor expression after experimental brain contusion in rat

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Neurovascular mechanisms of Alzheimer's neurodegeneration

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Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients

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Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

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Induction of angiogenesis by platelet-activating factor in the rat striatum

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Lentiviral vector-mediated, in vivo gene transfer to the tracheobronchial tree in fetal rabbits

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Gene expression changes by amyloid beta peptide-stimulated human postmortem brain microglia identify activation of multiple inflammatory processes

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Thrombin and prothrombin are expressed by neurons and glial cells and accumulate in neurofibrillary tangles in Alzheimer disease brain

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Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease

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12 December 2020

Minocycline or iNOS inhibition block 3-nitrotyrosine increases and blood-brain barrier leakiness in amyloid beta-peptide-injected rat hippocampus

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Pin1 protein associates with neuronal lipofuscin: potential consequences in age-related neurodegeneration.

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12 December 2020

Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocytes/macrophages

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Microvascular injury and blood-brain barrier leakage in Alzheimer's disease

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12 December 2020

Combined minocycline plus pyruvate treatment enhances effects of each agent to inhibit inflammation, oxidative damage, and neuronal loss in an excitotoxic animal model of Huntington's disease

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12 December 2020

Interleukin-13 enhances cyclooxygenase-2 expression in activated rat brain microglia: implications for death of activated microglia.

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12 December 2020

Corneal avascularity is due to soluble VEGF receptor-1

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12 December 2020

Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus.

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12 December 2020

Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia.

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12 December 2020

Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain.

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12 December 2020

Maternal exposure to low levels of corticosterone during lactation protects the adult offspring against ischemic brain damage.

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12 December 2020

Lrrk2 and chronic inflammation are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation.

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12 December 2020

Common inflammatory mechanisms in Lewy body disease and Alzheimer disease

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12 December 2020

Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-alpha in an animal model of inflamed Alzheimer's disease brain

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12 December 2020

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

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12 December 2020

Complement and cytokine gene expression in cultured microglial derived from postmortem human brains

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12 December 2020

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

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12 December 2020

Characterization of glial cultures from rapid autopsies of Alzheimer's and control patients.

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12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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12 December 2020

10.1523/JNEUROSCI.2888-08.2009

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19129379%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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19 January 2020

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