Stoichiometry of a pore mutation that abolishes picrotoxin-mediated antagonism of the GABAA receptor. (Q50644609)

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30 December 2019

title

Stoichiometry of a pore mutation that abolishes picrotoxin-mediated antagonism of the GABAA receptor (English)

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30 December 2019

4

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30 December 2019

author name string

Anna Sedelnikova

1

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30 December 2019

Brian E Erkkila

2

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30 December 2019

Holly Harris

3

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30 December 2019

David S Weiss

5

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30 December 2019

language of work or name

English

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publication date

21 September 2006

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30 December 2019

published in

Journal of Physiology

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30 December 2019

volume

577

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30 December 2019

issue

Pt 2

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30 December 2019

page(s)

569-577

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Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement

30 December 2019

cites work

1 reference

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A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits.

21 January 2018

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Consequence of the presence of two different beta subunit isoforms in a GABA(A) receptor

21 January 2018

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Two novel residues in M2 of the gamma-aminobutyric acid type A receptor affecting gating by GABA and picrotoxin affinity.

21 January 2018

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Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism

21 January 2018

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Picrotoxin antagonism of the inhibition of interneurons by glycine.

21 January 2018

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Identification of a novel residue within the second transmembrane domain that confers use-facilitated block by picrotoxin in glycine alpha 1 receptors.

21 January 2018

1 reference

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On the interaction of picrotoxin with GABA and glycine in the spinal cord.

21 January 2018

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GABA-picrotoxin interaction in the mammalian central nervous system.

21 January 2018

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Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABA rho 1 receptor

21 January 2018

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A picrotoxin-specific conformational change in the glycine receptor M2-M3 loop

21 January 2018

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Antagonism of GABA by picrotoxin in the feline cerebral cortex

21 January 2018

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Blockade of gamma-aminobutyric acid-gated chloride current in frog sensory neurons by picrotoxin.

21 January 2018

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Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.

21 January 2018

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Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.

21 January 2018

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Structure and gating mechanism of the acetylcholine receptor pore

21 January 2018

1 reference

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On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat.

21 January 2018

1 reference

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A single beta subunit M2 domain residue controls the picrotoxin sensitivity of alphabeta heteromeric glycine receptor chloride channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.120287

Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.120287

Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block

21 January 2018

1 reference

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Chloride channels of glycine and GABA receptors with blockers: Monte Carlo minimization and structure-activity relationships

21 January 2018

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Individual properties of the two functional agonist sites in GABA(A) receptors.

21 January 2018

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Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors.

29 September 2018

1 reference

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Stoichiometry and assembly of a recombinant GABAA receptor subtype.

29 September 2018

1 reference

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Stoichiometry of a recombinant GABAA receptor.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890441

Point mutations in the M2 region of the alpha, beta, or gamma subunit of the GABAA channel that abolish block by picrotoxin.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890441

Rapid insertional mutagenesis of DNA by polymerase chain reaction (PCR).

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890441

The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1890441

Nonlinear Regression Analysis and Its Applications

29 September 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.120287

Bicuculline and picrotoxin block gamma-aminobutyric acid-gated Cl- conductance by different mechanisms

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16990398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Studies on the mechanism of action of picrotoxinin and other convulsants at the crustacean muscle GABA receptor.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16990398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The “mixed” effect of picrotoxin on the GABA dose/conductance relation recorded from lobster muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16990398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2006.120287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990398%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PMC publication ID

1890441

0 references

1 reference