Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis. (Q50685651)

17 March 2018

title

Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis. (English)

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17 March 2018

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Michael J Grybko

1

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17 March 2018

Jakub P Bartnik

2

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17 March 2018

Georjeana A Wurth

3

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17 March 2018

Arun T Pores-Fernando

4

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17 March 2018

Adam Zweifach

5

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17 March 2018

language of work or name

English

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publication date

2 May 2007

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17 March 2018

Journal of Biological Chemistry

published in

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17 March 2018

volume

282

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17 March 2018

issue

25

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17 March 2018

page(s)

18009-18017

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17 March 2018

Two distinct action mechanisms of immunophilin-ligand complexes for the blockade of T-cell activation

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Antigen-receptor interaction requirement for conjugate formation and lethal-hit triggering by cytotoxic T lymphocytes can be bypassed by protein kinase C activators and Ca2+ ionophores

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Cross-talk with Ca(2+) influx does not underlie the role of extracellular signal-regulated kinases in cytotoxic T lymphocyte lytic granule exocytosis

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Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing

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Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor

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Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role

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A novel cytotoxic T lymphocyte activation assay. Optimized conditions for antigen receptor triggered granule enzyme secretion

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Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle.

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21 January 2018

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Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells

21 January 2018

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Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis

21 January 2018

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21 January 2018

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Dephosphorylation of microtubule-associated protein 2, tau factor, and tubulin by calcineurin.

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M702222200

1 reference

17 March 2018

PubMed ID

17478429

1 reference

17 March 2018