A live cell, image-based approach to understanding the enzymology and pharmacology of 2-bromopalmitate and palmitoylation. (Q50707844)

18 March 2018

title

A live cell, image-based approach to understanding the enzymology and pharmacology of 2-bromopalmitate and palmitoylation. (English)

1 reference

18 March 2018

author name string

Ivana Mikic

1

1 reference

18 March 2018

Sonia Planey

2

1 reference

18 March 2018

Jun Zhang

3

1 reference

18 March 2018

Carolina Ceballos

4

1 reference

18 March 2018

Terri Seron

5

1 reference

18 March 2018

Benedikt von Massenbach

6

1 reference

18 March 2018

Rachael Watson

7

1 reference

18 March 2018

Scott Callaway

8

1 reference

18 March 2018

Patrick M McDonough

9

1 reference

18 March 2018

Jeffrey H Price

10

1 reference

18 March 2018

Edward Hunter

11

1 reference

18 March 2018

David Zacharias

12

1 reference

18 March 2018

language of work or name

English

0 references

publication date

1 January 2006

1 reference

18 March 2018

published in

Methods in Enzymology

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18 March 2018

volume

414

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18 March 2018

page(s)

150-187

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18 March 2018

H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway

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Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation

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7 January 2021

Identification of PSD-95 palmitoylating enzymes

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7 January 2021

Surface density determination in membranes by fluorescence energy transfer

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7 January 2021

Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs

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7 January 2021

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7 January 2021

The 25 kDa synaptosomal-associated protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS

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7 January 2021

Characterization and partial purification of protein fatty acyltransferase activity from rat liver

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7 January 2021

Palmitoylation regulates regulators of G-protein signaling (RGS) 16 function. I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylation of an internal cysteine residue

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7 January 2021

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7 January 2021

Sequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling

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7 January 2021

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins

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7 January 2021

Resolving schizophrenia's CATCH22

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7 January 2021

A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65

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7 January 2021

Presynaptic trafficking of synaptotagmin I is regulated by protein palmitoylation

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7 January 2021

Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11.

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7 January 2021

The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ

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7 January 2021

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Galpha(s) is palmitoylated at the N-terminal glycine

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Characterization of the palmitoylation domain of SNAP-25

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A cell-specific, prenylation-independent mechanism regulates targeting of type II RACs

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Structure-activity studies of cerulenin analogues as protein palmitoylation inhibitors

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Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species

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The N-terminal SH4 region of the Src family kinase Fyn is modified by methylation and heterogeneous fatty acylation: role in membrane targeting, cell adhesion, and spreading

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7 January 2021

Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction

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7 January 2021

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Targeting of neuromodulin (GAP-43) fusion proteins to growth cones in cultured rat embryonic neurons

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7 January 2021

Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

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Agonist stimulation increases the turnover rate of beta 2AR-bound palmitate and promotes receptor depalmitoylation

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7 January 2021

Activation of the beta(2)-adrenergic receptor-Galpha(s) complex leads to rapid depalmitoylation and inhibition of repalmitoylation of both the receptor and Galpha(s).

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7 January 2021

Reaction path of protein farnesyltransferase at atomic resolution

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7 January 2021

SNAP-25 traffics to the plasma membrane by a syntaxin-independent mechanism

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7 January 2021

Loss of ZDHHC15 expression in a woman with a balanced translocation t(X;15)(q13.3;cen) and severe mental retardation.

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7 January 2021

Toward objective selection of representative microscope images

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7 January 2021

Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

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7 January 2021

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7 January 2021

Lipid-dependent Targeting of G Proteins into Rafts

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Statistics of assay validation in high throughput cell imaging of nuclear factor kappaB nuclear translocation.

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Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia

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7 January 2021

Crystal structure of the Aequorea victoria green fluorescent protein

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7 January 2021

Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor

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7 January 2021

Palmitoylation regulates regulator of G-protein signaling (RGS) 16 function. II. Palmitoylation of a cysteine residue in the RGS box is critical for RGS16 GTPase accelerating activity and regulation of Gi-coupled signalling

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7 January 2021

The structural basis for spectral variations in green fluorescent protein

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7 January 2021

Getting into position: the catalytic mechanisms of protein ubiquitylation

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7 January 2021

Identification of a palmitic acid-modified form of human Sonic hedgehog

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7 January 2021

Advances in molecular labeling, high throughput imaging and machine intelligence portend powerful functional cellular biochemistry tools

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7 January 2021

N-myristoyltransferase

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7 January 2021

Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins

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7 January 2021

Review: nuclear events in apoptosis

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7 January 2021

Mutagenesis of palmitoylation sites in endothelial nitric oxide synthase identifies a novel motif for dual acylation and subcellular targeting

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7 January 2021

An acylation cycle regulates localization and activity of palmitoylated Ras isoforms

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7 January 2021

Objective evaluation of differences in protein subcellular distribution

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7 January 2021

Protein prenylation: a pivotal posttranslational process

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7 January 2021

The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase

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7 January 2021

Mutations that suppress the thermosensitivity of green fluorescent protein.

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7 January 2021

Recent advances in the study of prenylated proteins

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7 January 2021

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

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7 January 2021

Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43.

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7 January 2021

Palmitoylation of intracellular signaling proteins: regulation and function

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7 January 2021

Fluorescence energy transfer in two dimensions. A numeric solution for random and nonrandom distributions

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7 January 2021

Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity

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7 January 2021

N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4.

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7 January 2021

Synaptobrevin 2 is palmitoylated in synaptic vesicles prepared from adult, but not from embryonic brain.

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7 January 2021

Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25

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7 January 2021

Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

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7 January 2021

Structural basis of spectral shifts in the yellow-emission variants of green fluorescent protein

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7 January 2021

Crystal structure and photodynamic behavior of the blue emission variant Y66H/Y145F of green fluorescent protein

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7 January 2021

Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein

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7 January 2021

Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids.

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7 January 2021

Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane

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7 January 2021

An analytic solution to the Förster energy transfer problem in two dimensions

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7 January 2021

Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association

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7 January 2021

The molecular structure of green fluorescent protein

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7 January 2021

Palmitoylation supports assembly and function of integrin-tetraspanin complexes

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7 January 2021

Theory for establishing proximity relations in biological membranes by excitation energy transfer measurements

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7 January 2021

Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement

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Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

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7 January 2021

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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7 January 2021

Calculation of resonance energy transfer in crowded biological membranes

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7 January 2021

The neuronal growth-associated protein GAP-43 induces filopodia in non-neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2914010-0

7 January 2021

A membrane-targeting signal in the amino terminus of the neuronal protein GAP-43.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2914010-0

7 January 2021

10.1016/S0076-6879(06)14010-0

Identifiers

DOI

1 reference

18 March 2018

PubMed ID

17110192

1 reference

18 March 2018