Reaction path of protein farnesyltransferase at atomic resolution (Q27639762)

Mechanistic studies of rat protein farnesyltransferase indicate an associative transition state

21 April 2017

1 reference

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

21 April 2017

1 reference

Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate

21 April 2017

1 reference

Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue

21 April 2017

1 reference

The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures

21 April 2017

1 reference

Functional analysis of microphthalmia-associated transcription factor in pigment cell-specific transcription of the human tyrosinase family genes

21 April 2017

1 reference

X-ray crystal structures of 70S ribosome functional complexes

21 April 2017

1 reference

Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution

21 April 2017

1 reference

Allosteric regulation of substrate binding and product release in geranylgeranyltransferase type II

21 April 2017

1 reference

The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics

21 April 2017

1 reference

3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency

21 April 2017

1 reference

Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships

21 April 2017

1 reference

Blocking oncogenic Ras signaling for cancer therapy

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Farnesyl transferase inhibitors: a novel targeted tnerapy for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Current status of clinical trials of farnesyltransferase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Yeast protein farnesyltransferase: a pre-steady-state kinetic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Differential prenyl pyrophosphate binding to mammalian protein geranylgeranyltransferase-I and protein farnesyltransferase and its consequence on the specificity of protein prenylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

NMR studies of novel inhibitors bound to farnesyl-protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

The diversity of Rab proteins in vesicle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Single prenyl-binding site on protein prenyl transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

21 January 2018

CaaX converting enzymes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

Yeast protein farnesyltransferase. Site-directed mutagenesis of conserved residues in the beta-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

7 January 2021

Mutational analysis of conserved residues of the beta-subunit of human farnesyl:protein transferase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

7 January 2021

Farnesyl protein transferase: identification of K164 alpha and Y300 beta as catalytic residues by mutagenesis and kinetic studies

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

7 January 2021

Substrate binding is required for release of product from mammalian protein farnesyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

7 January 2021

Conformation of a heptapeptide substrate bound to protein farnesyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00986

7 January 2021

Dimensions Publication ID

Identifiers

DOI

10.1038/NATURE00986

0 references

1000498088

0 references

Fatcat ID

release_7xgrea4a4vdh5nvzjidhuznawm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7xgrea4a4vdh5nvzjidhuznawm

24 November 2022