Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test. (Q50891308)

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scientific article published on 15 August 2007

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English	Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test.	scientific article published on 15 August 2007

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3 January 2020

Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test (English)

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3 January 2020

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Alberto C Costa

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3 January 2020

Jonah J Scott-McKean

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3 January 2020

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Melissa R Stasko

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15 August 2007

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3 January 2020

Neuropsychopharmacology

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3 January 2020

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3 January 2020

1624-1632

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3 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.npp.1301535

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Dementia of Alzheimer's disease and other neurodegenerative disorders--memantine, a new hope

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Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons

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Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

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Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome.

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Age-related deficits in context discrimination learning in Ts65Dn mice that model Down syndrome and Alzheimer's disease.

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Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function.

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Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

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