Molecular requirements for lineage commitment in the thymus--antibody-mediated receptor engagements reveal a central role for lck in lineage decisions. (Q51093045)

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scientific article published in October 1998

Language	Label	Description	Also known as
English	Molecular requirements for lineage commitment in the thymus--antibody-mediated receptor engagements reveal a central role for lck in lineage decisions.	scientific article published in October 1998

Statements

scholarly article

1 reference

Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

1 reference

Europe PubMed Central

Molecular requirements for lineage commitment in the thymus--antibody-mediated receptor engagements reveal a central role for lck in lineage decisions. (English)

1 reference

Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

cell fate commitment

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based on heuristic

inferred from title

5

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Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

author name string

Basson MA

1

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Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

Bommhardt U

2

1 reference

Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

Mee PJ

3

1 reference

Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

Tybulewicz VL

4

1 reference

Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

publication date

1 October 1998

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Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

Immunological Reviews

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Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

165

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Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

181-194

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Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

The nature of the peptide/MHC ligand involved in positive selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Specific recognition of thymic self-peptides induces the positive selection of cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Mechanisms of transmembrane signalling in human T cell activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

T-cell-receptor affinity and thymocyte positive selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Making the T cell receptor go the distance: a topological view of T cell activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

T-cell signaling: the importance of receptor clustering

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Kinetics and extent of T cell activation as measured with the calcium signal

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental program

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Cellular and biochemical requirements for thymocyte negative selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

T cell receptor antagonist peptides induce positive selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Evidence for a differential avidity model of T cell selection in the thymus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Mature T cell reactivity altered by peptide agonist that induces positive selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

T cell receptor antagonists and partial agonists

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

The MHC reactivity of the T cell repertoire prior to positive and negative selection.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

CD8 is needed for development of cytotoxic T cells but not helper T cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Essential flexibility in the T-cell recognition of antigen

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Altered T cell receptor ligands trigger a subset of early T cell signals

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

CD8 lineage commitment in the absence of CD8.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Partial signaling by CD8+ T cells in response to antagonist ligands

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

CD4 dependence of activation threshold and TCR signalling in mouse T lymphocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Differential signaling by lymphocyte antigen receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

The influence of the MAPK pathway on T cell lineage commitment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Antagonist peptide selects thymocytes expressing a class II major histocompatibility complex-restricted T cell receptor into the CD8 lineage

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

HLA-DO is an intracellular class II molecule with distinctive thymic expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

A novel class II MHC molecule with unusual tissue distribution

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

T Cells Can Be Activated by Peptides That Are Unrelated in Sequence to Their Selecting Peptide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Participation of CD4 coreceptor molecules in T-cell repertoire selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Identification of a naturally occurring ligand for thymic positive selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

T-cell selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Positive selection of T cells induced by viral delivery of neopeptides to the thymus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01239.X

21 January 2018

Identifiers

10.1111/J.1600-065X.1998.TB01239.X

1 reference

Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

1 reference

Europe PubMed Central

29 March 2018

http://europepmc.org/abstract/MED/9850861

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