A soluble form of GAS1 inhibits tumor growth and angiogenesis in a triple negative breast cancer model. (Q51130082)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992044%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

A soluble form of GAS1 inhibits tumor growth and angiogenesis in a triple negative breast cancer model (English)

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21 March 2020

3

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21 March 2020

author name string

Adriana Jiménez

1

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21 March 2020

Adolfo López-Ornelas

2

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21 March 2020

Lorenza González-Mariscal

4

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21 March 2020

Rosa O González

5

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21 March 2020

José Segovia

6

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21 March 2020

language of work or name

English

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publication date

30 June 2014

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Experimental Cell Research

21 March 2020

published in

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21 March 2020

volume

327

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21 March 2020

issue

2

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21 March 2020

page(s)

307-317

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21 March 2020

1 reference

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