Expanding Substrate Promiscuity by Engineering a Novel Adenylating-Methylating NRPS Bifunctional Enzyme. (Q51351857)

4 April 2018

title

Expanding Substrate Promiscuity by Engineering a Novel Adenylating-Methylating NRPS Bifunctional Enzyme. (English)

1 reference

4 April 2018

author

Sylvie Garneau-Tsodikova

series ordinal

2

1 reference

4 April 2018

author name string

Sanjib K Shrestha

series ordinal

1

1 reference

4 April 2018

publication date

29 April 2016

1 reference

4 April 2018

published in

ChemBioChem

1 reference

4 April 2018

volume

17

1 reference

4 April 2018

issue

14

1 reference

4 April 2018

page(s)

1328-1332

1 reference

4 April 2018

Nonribosomal peptides: from genes to products

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

The A9 core sequence from NRPS adenylation domain is relevant for thioester formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Recent developments in bisintercalator natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

A nonradioactive high-throughput assay for screening and characterization of adenylation domains for nonribosomal peptide combinatorial biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Characterization of the formation of the pyrrole moiety during clorobiocin and coumermycin A1 biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Protein assembly line components in prodigiosin biosynthesis: characterization of PigA,G,H,I,J.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Characterization of TioF, a tryptophan 2,3-dioxygenase involved in 3-hydroxyquinaldic acid formation during thiocoraline biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

A new scaffold of an old protein fold ensures binding to the bisintercalator thiocoraline

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Characterization of TioQ, a type II thioesterase from the thiocoraline biosynthetic cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

KtzJ-dependent serine activation and O-methylation by KtzH for kutznerides biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Role of MbtH-like proteins in the adenylation of tyrosine during aminocoumarin and vancomycin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Non-ribosomal propeptide precursor in nocardicin A biosynthesis predicted from adenylation domain specificity dependent on the MbtH family protein NocI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

MbtH-like proteins as integral components of bacterial nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

N-acylation during glidobactin biosynthesis by the tridomain nonribosomal peptide synthetase module GlbF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

In vitro characterization of echinomycin biosynthesis: formation and hydroxylation of L-tryptophanyl-S-enzyme and oxidation of (2S,3S) β-hydroxytryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Activation of the pacidamycin PacL adenylation domain by MbtH-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Enzymatic Evidence for a Revised Congocidine Biosynthetic Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Importance of the MbtH-like protein TioT for production and activation of the thiocoraline adenylation domain of TioK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

Adenylation and S-Methylation of Cysteine by the Bifunctional Enzyme TioN in Thiocoraline Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201600234

21 January 2018

Identifiers

DOI

10.1002/CBIC.201600234

1 reference

4 April 2018

PubMed ID

27128382

1 reference

4 April 2018