Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R⁻/⁻) mice. (Q51358907)

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scientific article published on 20 March 2012

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English	Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R⁻/⁻) mice.	scientific article published on 20 March 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R⁻/⁻) mice. (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

Francesco Potì

1

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Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

Christian Weber

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PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

7

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PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

author name string

Sara Costa

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PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

Valeria Bergonzini

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4 April 2018

http://europepmc.org/abstract/MED/22459073

Margherita Galletti

4

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PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

Elisa Pignatti

5

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4 April 2018

http://europepmc.org/abstract/MED/22459073

Jerzy-Roch Nofer

8

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PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

publication date

20 March 2012

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4 April 2018

http://europepmc.org/abstract/MED/22459073

Vascular Pharmacology

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4 April 2018

http://europepmc.org/abstract/MED/22459073

57

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http://europepmc.org/abstract/MED/22459073

1

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http://europepmc.org/abstract/MED/22459073

56-64

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http://europepmc.org/abstract/MED/22459073

Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes

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Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury

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FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells

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FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages.

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Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

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Influence of interferon-gamma on the extent and phenotype of diet-induced atherosclerosis in the LDLR-deficient mouse

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Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

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Transdifferentiation properties of adipocytes in the adipose organ

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An update on the role of markers of inflammation in atherosclerosis

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Diet and murine atherosclerosis

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Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions

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MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.

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Inflammation, atherosclerosis, and coronary artery disease

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The immune response in atherosclerosis: a double-edged sword

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Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice

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7 January 2021

S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate

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7 January 2021

FTY720, a sphingosine-1-phosphate receptor modulator, reverses high-fat diet-induced weight gain, insulin resistance and adipose tissue inflammation in C57BL/6 mice

1 reference

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7 January 2021

The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice.

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7 January 2021

Sphingosine-1-phosphate receptor 3 promotes recruitment of monocyte/macrophages in inflammation and atherosclerosis

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Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis

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7 January 2021

Sphingosine-1-phosphate analogue FTY720 causes lymphocyte redistribution and hypercholesterolemia in ApoE-deficient mice.

1 reference

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7 January 2021

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

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7 January 2021

Preferential Sphingosine-1-Phosphate Enrichment and Sphingomyelin Depletion Are Key Features of Small Dense HDL3 Particles

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7 January 2021

High-density lipoprotein: a potent inhibitor of inflammation

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High-density lipoprotein, sphingosine 1-phosphate, and atherosclerosis

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Atheroprotective effects of high-density lipoprotein-associated lysosphingolipids

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7 January 2021

FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice.

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7 January 2021

Macrophages, inflammation, and insulin resistance

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7 January 2021

Markers of inflammation and risk of coronary heart disease.

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Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720.

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7 January 2021

Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis

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NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion

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Role of Interferon-γ in Hypercholesterolemia-Induced Leukocyte–Endothelial Cell Adhesion

1 reference

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Role of interleukin 12 in hypercholesterolemia-induced inflammation

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Dietary cholesterol worsens adipose tissue macrophage accumulation and atherosclerosis in obese LDL receptor-deficient mice

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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

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High-density lipoproteins, inflammation and oxidative stress

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Obesity is associated with macrophage accumulation in adipose tissue

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Beneficial effects of alternate dietary regimen on liver inflammation, atherosclerosis and renal activation

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The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo

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Correlation of high density lipoprotein (HDL)-associated sphingosine 1-phosphate with serum levels of HDL-cholesterol and apolipoproteins

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7 January 2021

Identifiers

10.1016/J.VPH.2012.03.003

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22459073

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