Factors predicting therapeutic efficacy of combination treatment with sitagliptin and metformin in type 2 diabetic patients: the COSMETIC study. (Q51367458)

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scientific article published in August 2012

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English	Factors predicting therapeutic efficacy of combination treatment with sitagliptin and metformin in type 2 diabetic patients: the COSMETIC study.	scientific article published in August 2012

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13 February 2020

Factors predicting therapeutic efficacy of combination treatment with sitagliptin and metformin in type 2 diabetic patients: the COSMETIC study (English)

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13 February 2020

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Jee Hyun An

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Hayley Shin

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Ah Reum Khang

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Yenna Lee

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Hwa Young Ahn

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Ji Won Yoon

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Seon Mee Kang

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Young Min Cho

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Kyong Soo Park

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Hak Chul Jang

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publication date

1 August 2012

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Clinical Endocrinology

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215-223

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13 February 2020

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Efficacy and safety of sitagliptin monotherapy in Japanese patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Efficacy and safety of monotherapy of sitagliptin compared with metformin in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Effect of adding sitagliptin, a dipeptidyl peptidase-4 inhibitor, to metformin on 24-h glycaemic control and beta-cell function in patients with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1.

1 reference

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21 January 2018

Enhanced secretion of glucagon-like peptide 1 by biguanide compounds

1 reference

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Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Efficacy and safety of sitagliptin and metformin as initial combination therapy and as monotherapy over 2 years in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Predictive clinical parameters for the therapeutic efficacy of sitagliptin in korean type 2 diabetes mellitus

1 reference

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21 January 2018

Retrospective analysis on the efficacy, safety and treatment failure group of sitagliptin for mean 10-month duration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

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21 January 2018

Insulin Secretion in Response to Glycemic Stimulus: Relation of Delayed Initial Release to Carbohydrate intolerance in Mild Diabetes Mellitus*

1 reference

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21 January 2018

Body mass index and cardiovascular disease in the Asia-Pacific Region: an overview of 33 cohorts involving 310 000 participants

1 reference

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The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis

1 reference

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21 January 2018

Robust improvements in fasting and prandial measures of beta-cell function with vildagliptin in drug-naïve patients: analysis of pooled vildagliptin monotherapy database

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Effects of low intensity exercise therapy on early phase insulin secretion in overweight subjects with impaired glucose tolerance and type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Biochemical and molecular mechanisms in the development of diabetic vascular complications

1 reference

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21 January 2018

Oxidative stress and diabetic vascular complications

1 reference

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21 January 2018

Pancreatic B-cell function is altered by oxidative stress induced by acute hyperglycaemia

1 reference

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21 January 2018

Glucolipotoxicity and beta cells in type 2 diabetes mellitus: target for durable therapy?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

New aspects of an old drug: metformin as a glucagon-like peptide 1 (GLP-1) enhancer and sensitiser

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Comparison of tests of beta-cell function across a range of glucose tolerance from normal to diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Continuous infusion of glucose with model assessment: measurement of insulin resistance and beta-cell function in man.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

The heritability of beta cell function parameters in a mixed meal test design

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Impaired beta-cell sensitivity to glucose and maximal insulin secretory capacity in adolescents with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Risk assessment by post-challenge plasma glucose, insulin response ratio, and other indices of insulin resistance and/or secretion for predicting the development of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Relationships between insulin secretion after intravenous and oral glucose administration in subjects with glucose tolerance ranging from normal to overt diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Meal composition affects insulin secretion in women with type 2 diabetes: a comparison with healthy controls. The Hoorn prandial study

1 reference

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21 January 2018

Assessment of beta-cell function during the oral glucose tolerance test by a minimal model of insulin secretion.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Reduced serum dipeptidyl peptidase-IV after metformin and pioglitazone treatments

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Inhibition of dipeptidyl peptidase IV activity by oral metformin in Type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

Effect of Single Oral Doses of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Incretin and Plasma Glucose Levels after an Oral Glucose Tolerance Test in Patients with Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2011.04240.X

21 January 2018

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