The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes. (Q51488380)

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20 December 2019

title

The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes (English)

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20 December 2019

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20 December 2019

Pietro Formisano

15

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20 December 2019

Gregoryalexander Raciti

3

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20 December 2019

Olga Vaccaro

9

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20 December 2019

author name string

R Valentino

1

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20 December 2019

G A Lupoli

2

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20 December 2019

F Oriente

4

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20 December 2019

E Farinaro

5

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20 December 2019

E Della Valle

6

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20 December 2019

M Salomone

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20 December 2019

G Riccardi

8

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20 December 2019

G Donnarumma

10

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20 December 2019

M L Hribal

12

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20 December 2019

M Cardellini

13

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20 December 2019

C Miele

14

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20 December 2019

F Beguinot

16

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20 December 2019

publication date

5 October 2006

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20 December 2019

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20 December 2019

volume

49

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20 December 2019

issue

12

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20 December 2019

page(s)

3058-3066

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Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism

20 December 2019

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0455-5

Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0455-5

Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha-induced apoptosis

21 January 2018

1 reference

12 December 2020

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

12 December 2020

Protein kinase C (PKC)-alpha activation inhibits PKC-zeta and mediates the action of PED/PEA-15 on glucose transport in the L6 skeletal muscle cells

1 reference

12 December 2020

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

12 December 2020

Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function

1 reference

12 December 2020

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

12 December 2020

Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.

1 reference

12 December 2020

RSK2 activity is regulated by its interaction with PEA-15

1 reference

12 December 2020

Location of the granulocyte‐specific antigen LAN on the Fc‐receptor III

1 reference

12 December 2020

Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects.

1 reference

12 December 2020

PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus

1 reference

12 December 2020

Method for large scale isolation, culture and cryopreservation of human monocytes suitable for chemotaxis, cellular adhesion assays, macrophage and dendritic cell differentiation

1 reference

12 December 2020

Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action

1 reference

12 December 2020

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

1 reference

12 December 2020

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

12 December 2020

Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action

1 reference

12 December 2020

Cellular expression, developmental regulation, and phylogenic conservation of PEA-15, the astrocytic major phosphoprotein and protein kinase C substrate.

1 reference

12 December 2020

C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance.

1 reference

12 December 2020

Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them

1 reference

12 December 2020

Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells.

1 reference

12 December 2020

Follow-up report on the diagnosis of diabetes mellitus

1 reference

12 December 2020

Parental history of diabetes in a population-based study

1 reference

12 December 2020

The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy

1 reference

12 December 2020

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

1 reference

12 December 2020

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

1 reference

12 December 2020

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

1 reference

12 December 2020

The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis

1 reference

12 December 2020

The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human

1 reference

12 December 2020

Insulin and amylin release are both diminished in first-degree relatives of subjects with type 2 diabetes

1 reference

12 December 2020

The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients

1 reference

12 December 2020

Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus

1 reference

12 December 2020

Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15

1 reference

12 December 2020

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

1 reference

12 December 2020

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

12 December 2020