Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models. (Q51541906)

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scientific article published on 21 February 2012

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English	Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models.	scientific article published on 21 February 2012

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scholarly article

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models. (English)

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

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insulin resistance

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based on heuristic

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author name string

Y D Kim

1

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

Y H Kim

2

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

Y M Cho

3

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

D K Kim

4

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

S W Ahn

5

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

J M Lee

6

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

D Chanda

7

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

M Shong

8

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

C H Lee

9

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

H S Choi

10

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

publication date

21 February 2012

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

55

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

5

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Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

1482-1494

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

https://scigraph.springernature.com/pub.10.1007/s00125-012-2494-4

0 references

Insulin resistance, inflammation, and non-alcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Interleukin-6 induces cellular insulin resistance in hepatocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

The dual function of hepatic SOCS3 in insulin resistance in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Human IL6 enhances leptin action in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Metformin reverses fatty liver disease in obese, leptin-deficient mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Role of AMP-activated protein kinase in mechanism of metformin action

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase-Dependent Regulation of the Orphan Nuclear Receptor SHP

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

AMPK: an emerging drug target for diabetes and the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Structure and function of the atypical orphan nuclear receptor small heterodimer partner

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Molecular basis of endocrine regulation by orphan nuclear receptor Small Heterodimer Partner

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Hepatocyte growth factor family negatively regulates hepatic gluconeogenesis via induction of orphan nuclear receptor small heterodimer partner in primary hepatocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Sodium arsenite induces orphan nuclear receptor SHP gene expression via AMP-activated protein kinase to inhibit gluconeogenic enzyme gene expression.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Regulation of suppressor of cytokine signaling 3 (SOC3) by growth hormone in pro-B cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Analysis of SOCS-3 promoter responses to interferon gamma

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes. Preservation of cytokine signaling during fever

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Control of gluconeogenic genes during intense/prolonged exercise: hormone-independent effect of muscle-derived IL-6 on hepatic tissue and PEPCK mRNA.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Interleukin-6 and diabetes: the good, the bad, or the indifferent?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3).

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Adiponectin reduces C-reactive protein expression and downregulates STAT3 phosphorylation induced by IL-6 in HepG2 cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2494-4

21 January 2018

Metformin modulates insulin post-receptor signaling transduction in chronically insulin-treated Hep G2 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22349108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine and carbohydrate responses to interleukin-6 in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22349108

12 December 2020

based on heuristic

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Interleukin-6 stimulates gluconeogenesis in primary cultures of rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22349108

12 December 2020

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Interleukin 6 stimulates hepatic glucose release from prelabeled glycogen pools

1 reference

https://pubmed.ncbi.nlm.nih.gov/22349108

12 December 2020

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Dose-dependent effects of recombinant human interleukin-6 on glucose regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22349108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-012-2494-4

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

1 reference

Europe PubMed Central

6 April 2018

http://europepmc.org/abstract/MED/22349108

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