Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition. (Q51696345)

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scientific article published on 17 June 2016

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English	Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition.	scientific article published on 17 June 2016

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition. (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

1 reference

based on heuristic

inferred from title

drug interaction

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Prabhakar Koiram

object named as

Prabhakar Rajanna

6

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object named as

Yurong Lai

1

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author name string

Sandhya Mandlekar

2

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Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Hong Shen

3

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Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Vinay K Holenarsipur

4

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Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Robert Langish

5

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Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Senthilkumar Murugesan

7

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PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Nilesh Gaud

8

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PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Sabariya Selvam

9

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9 April 2018

http://europepmc.org/abstract/MED/27317801

Onkar Date

10

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9 April 2018

http://europepmc.org/abstract/MED/27317801

Yaofeng Cheng

11

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9 April 2018

http://europepmc.org/abstract/MED/27317801

Petia Shipkova

12

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PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Jun Dai

13

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9 April 2018

http://europepmc.org/abstract/MED/27317801

William G Humphreys

14

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Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Punit Marathe

15

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9 April 2018

http://europepmc.org/abstract/MED/27317801

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publication date

17 June 2016

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PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

Journal of Pharmacology and Experimental Therapeutics

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9 April 2018

http://europepmc.org/abstract/MED/27317801

358

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9 April 2018

http://europepmc.org/abstract/MED/27317801

3

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http://europepmc.org/abstract/MED/27317801

397-404

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9 April 2018

http://europepmc.org/abstract/MED/27317801

Cyclosporine A, but not tacrolimus, shows relevant inhibition of organic anion-transporting protein 1B1-mediated transport of atorvastatin

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The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose range

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Coproporphyrin I and III excretion in bile and urine

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Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics

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Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans

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Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment

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Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics

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Liver-specific distribution of rosuvastatin in rats: comparison with pravastatin and simvastatin

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Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake

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Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

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The current state of serum biomarkers of hepatotoxicity.

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Global analysis of genetic variation in SLCO1B1.

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Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin

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Drug-drug interaction studies: regulatory guidance and an industry perspective

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Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species

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Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation.

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Evaluation of rosuvastatin as an organic anion transporting polypeptide (OATP) probe substrate: in vitro transport and in vivo disposition in cynomolgus monkeys.

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21 January 2018

Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation

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Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption

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Long-lasting inhibitory effects of saquinavir and ritonavir on OATP1B1-mediated uptake

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Transporter studies in drug development: experience to date and follow-up on decision trees from the International Transporter Consortium

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Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver

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Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS).

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Rotor's syndrome

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Transporter-mediated drug--drug interactions involving OATP substrates: predictions based on in vitro inhibition studies.

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Identifiers

10.1124/JPET.116.234914

1 reference

Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 April 2018

http://europepmc.org/abstract/MED/27317801

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