The challenge of immunogenicity in the quest for induced pluripotency. (Q51776242)

12 April 2018

title

The challenge of immunogenicity in the quest for induced pluripotency. (English)

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12 April 2018

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Paul J Fairchild

1

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12 April 2018

publication date

1 December 2010

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12 April 2018

Nature Reviews Immunology

published in

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12 April 2018

volume

10

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12 April 2018

issue

12

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12 April 2018

page(s)

868-875

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12 April 2018

Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

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Embryonic stem cell lines derived from human blastocysts

21 January 2018

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Derive and conquer: sourcing and differentiating stem cells for therapeutic applications.

31 March 2020

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Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer.

31 March 2020

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Cell replacement therapy and the evasion of destructive immunity

31 March 2020

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

31 March 2020

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Epigenetic memory in induced pluripotent stem cells

31 March 2020

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Generation of germline-competent induced pluripotent stem cells

31 March 2020

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iPS cells produce viable mice through tetraploid complementation

31 March 2020

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Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

31 March 2020

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Reprogramming of pancreatic beta cells into induced pluripotent stem cells

31 March 2020

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Generation of induced pluripotent stem cells from human blood

31 March 2020

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Generation of pluripotent stem cells from adult mouse liver and stomach cells

31 March 2020

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Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors

31 March 2020

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Generation of induced pluripotent stem cell lines from adult rat cells

31 March 2020

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Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts

31 March 2020

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

31 March 2020

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Reprogramming of human somatic cells to pluripotency with defined factors

31 March 2020

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Induced pluripotent stem cell lines derived from human somatic cells

31 March 2020

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The promise of human induced pluripotent stem cells for research and therapy

31 March 2020

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Strategies and new developments in the generation of patient-specific pluripotent stem cells

31 March 2020

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Disease-specific induced pluripotent stem cells

31 March 2020

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Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells

31 March 2020

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Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

31 March 2020

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Generation of pluripotent stem cells from patients with type 1 diabetes

31 March 2020

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Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

31 March 2020

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Induced pluripotent stem cells from a spinal muscular atrophy patient

31 March 2020

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

31 March 2020

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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

31 March 2020

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Complete genetic correction of ips cells from Duchenne muscular dystrophy

31 March 2020

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Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

31 March 2020

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Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

31 March 2020

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Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

31 March 2020

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Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

31 March 2020

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Induced pluripotent stem cells derived from mouse models of lysosomal storage disorders

31 March 2020

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Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatment

31 March 2020

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Properties of anti-factor VIII inhibitor antibodies in hemophilia A patients

31 March 2020

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The systematic production of cells for cell therapies

31 March 2020

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HLA-haplotype banking and iPS cells

31 March 2020

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Transplantation tolerance in an age of induced pluripotency.

31 March 2020

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HLA DNA typing and transplantation

31 March 2020

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HLA-matching potential of an established human embryonic stem cell bank in China

31 March 2020

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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

31 March 2020

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Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2.

31 March 2020

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Cord blood transplantation: state of the art.

31 March 2020

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Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance

31 March 2020

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Variation in the safety of induced pluripotent stem cell lines

31 March 2020

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Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

31 March 2020

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A role for regulatory T cells in acceptance of ESC-derived tissues transplanted across an major histocompatibility complex barrier

31 March 2020

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A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts

31 March 2020

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Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts

31 March 2020

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Mixed chimerism and transplant tolerance

31 March 2020

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Mixed chimerism and tolerance without whole body irradiation in a large animal model

31 March 2020

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Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model

31 March 2020

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Human ES cells--haematopoiesis and transplantation strategies

31 March 2020

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Embryonic stem cells as an alternate marrow donor source: engraftment without graft-versus-host disease

31 March 2020

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Hematopoietic mixed chimerism derived from allogeneic embryonic stem cells prevents autoimmune diabetes mellitus in NOD mice.

31 March 2020

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Hematopoiesis from human embryonic stem cells: overcoming the immune barrier in stem cell therapies

31 March 2020

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Harnessing dendritic cells for the induction of transplantation tolerance

31 March 2020

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Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells

31 March 2020

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Generation of mature human myelomonocytic cells through expansion and differentiation of pluripotent stem cell-derived lin-CD34+CD43+CD45+ progenitors

31 March 2020

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Induction of Regulatory T Cells and Dominant Tolerance by Dendritic Cells Incapable of Full Activation

31 March 2020

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Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance

31 March 2020

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Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion

31 March 2020

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

31 March 2020

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Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells

31 March 2020

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Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

31 March 2020

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Successful induction of immune tolerance to enzyme replacement therapy in canine mucopolysaccharidosis I

31 March 2020

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Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

31 March 2020

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Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans

31 March 2020

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Induced pluripotent stem cells generated without viral integration

31 March 2020

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Generation of mouse induced pluripotent stem cells without viral vectors

31 March 2020

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Virus-free induction of pluripotency and subsequent excision of reprogramming factors

31 March 2020

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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

31 March 2020

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

31 March 2020

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Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc

31 March 2020

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Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells

31 March 2020

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Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

31 March 2020

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Generation of induced pluripotent stem cells using recombinant proteins

31 March 2020

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

31 March 2020

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Establishment in culture of pluripotential cells from mouse embryos

31 March 2020

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Hematopoietic colony-forming cells derived from human embryonic stem cells

31 March 2020

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Immune tolerance improves the efficacy of enzyme replacement therapy in canine mucopolysaccharidosis I.

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21107347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Industry Update: Latest developments in stem cell research and regenerative medicine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21107347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI2878

1 reference

12 April 2018

PubMed ID

21107347

1 reference

12 April 2018