Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins. (Q51784478)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29500195%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins (English)

1 reference

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19 March 2020

author name string

Elisabeth K Nyakatura

1

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19 March 2020

Samantha E Zak

2

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19 March 2020

Anna Z Wec

3

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19 March 2020

Daniel Hofmann

4

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19 March 2020

Sergey Shulenin

5

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19 March 2020

Russell R Bakken

6

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19 March 2020

M Javad Aman

7

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19 March 2020

Jonathan R Lai

10

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19 March 2020

language of work or name

English

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publication date

2 March 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29500195%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

19 March 2020

published in

1 reference

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19 March 2020

volume

293

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19 March 2020

issue

16

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19 March 2020

page(s)

6201-6211

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Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

19 March 2020

cites work

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7 September 2018

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Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.

7 September 2018

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7 September 2018

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Bispecific antibodies for viral immunotherapy

7 September 2018

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A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

7 September 2018

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A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses

7 September 2018

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Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

7 September 2018

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7 September 2018

Neglected filoviruses

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Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

7 September 2018

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Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

7 September 2018

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Discovery of an antibody for pan-ebolavirus therapy

7 September 2018

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Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

7 September 2018

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Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses.

7 September 2018

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Ebolavirus Evolution: Past and Present

7 September 2018

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Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

7 September 2018

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Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein.

7 September 2018

1 reference

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Mechanism of Binding to Ebola Virus Glycoprotein by the ZMapp, ZMAb, and MB-003 Cocktail Antibodies

7 September 2018

1 reference

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Structural basis for Marburg virus neutralization by a cross-reactive human antibody

7 September 2018

1 reference

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Mechanism of human antibody-mediated neutralization of Marburg virus

7 September 2018

1 reference

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Structures of protective antibodies reveal sites of vulnerability on Ebola virus

7 September 2018

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Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

7 September 2018

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Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail

7 September 2018

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Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

7 September 2018

1 reference

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Structural basis for differential neutralization of ebolaviruses

7 September 2018

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Protective efficacy of neutralizing monoclonal antibodies in a nonhuman primate model of Ebola hemorrhagic fever

7 September 2018

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Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease.

7 September 2018

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Ebola virus entry requires the host-programmed recognition of an intracellular receptor

7 September 2018

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A shared structural solution for neutralizing ebolaviruses

7 September 2018

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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

7 September 2018

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Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations

7 September 2018

1 reference

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A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry

7 September 2018

1 reference

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Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

7 September 2018

1 reference

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Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin.

7 September 2018

1 reference

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Antibody internalization studied using a novel IgG binding toxin fusion

7 September 2018

1 reference

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Covalent modifications of the ebola virus glycoprotein

7 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912469

Processing of the Ebola virus glycoprotein by the proprotein convertase furin

7 September 2018

1 reference

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The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing

7 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912469

7 September 2018

Identifiers

DOI

10.1074/JBC.RA117.001627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29500195%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29500195%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

29500195

1 reference