Role of Wnt signaling in the development of type 2 diabetes. (Q51793221)

12 April 2018

title

Role of Wnt signaling in the development of type 2 diabetes. (English)

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12 April 2018

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Michael Bordonaro

1

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12 April 2018

publication date

1 January 2009

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12 April 2018

published in

Vitamins and Hormones

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12 April 2018

volume

80

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12 April 2018

page(s)

563-581

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12 April 2018

Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

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Protection of pancreatic beta-cells: is it feasible?

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The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors

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TCF7L2 genetic defect and type 2 diabetes

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TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis

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Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

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A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development

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Glucagon-like peptide-2 activates beta-catenin signaling in the mouse intestinal crypt: role of insulin-like growth factor-I.

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Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans

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Assignment of the TCF-4 gene (TCF7L2) to human chromosome band 10q25.3

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Testing the gene or testing a variant? The case of TCF7L2

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

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WNT signalling is both an inducer and effector of glucagon-like peptide-1

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Wnt-signaling is maintained and adipogenesis inhibited by TNFalpha but not MCP-1 and resistin

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Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene

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Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

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Why diabetes patients are more prone to the development of colon cancer?

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The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus

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Wnt5b partially inhibits canonical Wnt/beta-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes

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Lessons from hereditary colorectal cancer

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Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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7 January 2021

Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate

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7 January 2021

Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation

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7 January 2021

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells

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7 January 2021

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

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Apoptosis and APC in colorectal tumorigenesis

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7 January 2021

Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells

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Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

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Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.

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7 January 2021

Wnt signaling regulates pancreatic beta cell proliferation

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7 January 2021

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

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7 January 2021

RETRACTED: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

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7 January 2021

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

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7 January 2021

Association of the APC tumor suppressor protein with catenins

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7 January 2021

HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells

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7 January 2021

Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling

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7 January 2021

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

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7 January 2021

Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells

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7 January 2021

Global and societal implications of the diabetes epidemic

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7 January 2021

10.1016/S0083-6729(08)00619-5

Identifiers

DOI

1 reference

12 April 2018

1 reference

12 April 2018