MDM2 309 polymorphism is associated with missed abortion. (Q51796850)

12 April 2018

title

MDM2 309 polymorphism is associated with missed abortion. (English)

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12 April 2018

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Yan Fang

1

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12 April 2018

Beihua Kong

2

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12 April 2018

Qifeng Yang

3

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12 April 2018

Daoxin Ma

4

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12 April 2018

Xun Qu

5

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12 April 2018

language of work or name

English

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publication date

26 February 2009

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12 April 2018

published in

Human Reproduction

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12 April 2018

volume

24

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12 April 2018

issue

6

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12 April 2018

page(s)

1346-1349

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12 April 2018

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

cites work

1 reference

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The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis

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The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma.

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Apoptosis in the first trimester human placenta: the role in maintaining immune privilege at the maternal-foetal interface and in the trophoblast remodelling

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Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

21 January 2018

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Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1alpha and Hdm2.

21 January 2018

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To be, or not to be, that is the question. Apoptosis in human trophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMREP%2FDEP044

MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMREP%2FDEP044

Oncogene and tumour suppressor gene products during trophoblast differentiation in the first trimester.

21 January 2018

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Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHUMREP%2FDEP044

p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis

21 January 2018

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MDM2 and MDM4: p53 regulators as targets in anticancer therapy

21 January 2018

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Mechanisms of 5-azacytidine (5AzC)-induced toxicity in the rat foetal brain

21 January 2018

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The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

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A functional p53-responsive intronic promoter is contained within the human mdm2 gene

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HUMREP/DEP044

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12 April 2018

PubMed ID

19246469

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12 April 2018