Ceramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I. (Q51803770)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Ceramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

N-acetyl dihydrosphingosine

30 December 2019

main subject

1 reference

ChEBI release 2020-05-28

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Amy B Ghering

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

21 September 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

2781-2788

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

The complex life of simple sphingolipids

30 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Ceramide in apoptosis: an overview and current perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Functions of ceramide in coordinating cellular responses to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Modulation of cell growth and differentiation by ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Accumulation of glucosylceramides in multidrug-resistant cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Ceramides modulate protein kinase C activity and perturb the structure of Phosphatidylcholine/Phosphatidylserine bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Kinase suppressor of Ras is ceramide-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

The structural requirements for ceramide activation of serine-threonine protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

The spatial organization of apolipoprotein A-I on the edge of discoidal high density lipoprotein particles: a mass specrometry study

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Role for ceramide in cell cycle arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Synthetic, non-natural sphingolipid analogs inhibit the biosynthesis of cellular sphingolipids, elevate ceramide and induce apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Lipid structure and not membrane structure is the major determinant in the regulation of protein kinase C by phosphatidylserine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Sphingosine kinase, sphingosine-1-phosphate, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Effects of enrichment of fibroblasts with unesterified cholesterol on the efflux of cellular lipids to apolipoprotein A-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Ceramide inhibition of mammalian phospholipase D1 and D2 activities is antagonized by phosphatidylinositol 4,5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Intracellular cholesterol mobilization involved in the ABCA1/apolipoprotein-mediated assembly of high density lipoprotein in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600380-JLR200

10.1194/JLR.M600380-JLR200

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16990644%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference