Elevated marrow inflammatory cells and osteoclasts in subchondral osteosclerosis in human knee osteoarthritis. (Q51818684)

13 April 2018

http://europepmc.org/abstract/MED/26250062

title

Elevated marrow inflammatory cells and osteoclasts in subchondral osteosclerosis in human knee osteoarthritis. (English)

1 reference

13 April 2018

http://europepmc.org/abstract/MED/26250062

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1

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31 May 2020

author name string

Amit Patel

2

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31 May 2020

Michael T Hirschmann

3

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31 May 2020

Geert I Pagenstert

4

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31 May 2020

Magdalena Müller-Gerbl

5

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31 May 2020

Victor Valderrabano

6

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31 May 2020

Thomas Hügle

7

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31 May 2020

publication date

6 August 2015

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13 April 2018

http://europepmc.org/abstract/MED/26250062

published in

Journal of Orthopaedic Research

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31 May 2020

volume

34

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31 May 2020

issue

2

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31 May 2020

page(s)

262-269

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In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model.

31 May 2020

cites work

1 reference

Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: an in vivo microfocal computed tomography study.

21 January 2018

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Bone remodelling in osteoarthritis

21 January 2018

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Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

21 January 2018

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Subchondral tibial bone mineral density predicts future joint space narrowing at the medial femoro-tibial compartment in patients with knee osteoarthritis.

21 January 2018

1 reference

Quantitative analysis of subchondral sclerosis of the tibia by bone texture parameters in knee radiographs: site-specific relationships with joint space width.

21 January 2018

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Subchondral bone remodeling is related to clinical improvement after joint distraction in the treatment of ankle osteoarthritis

21 January 2018

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Changes of density distribution of the subchondral bone plate after supramalleolar osteotomy for valgus ankle osteoarthritis

21 January 2018

1 reference

Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit

21 January 2018

1 reference

Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: possible role in subchondral bone sclerosis

21 January 2018

1 reference

Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone.

21 January 2018

1 reference

Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production

21 January 2018

1 reference

Elevated Dickkopf-2 levels contribute to the abnormal phenotype of human osteoarthritic osteoblasts

21 January 2018

1 reference

Regulation of subchondral bone osteoblast metabolism by cyclic compression

21 January 2018

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Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity

21 January 2018

1 reference

Overexpressed TGF-β in subchondral bone leads to mandibular condyle degradation

21 January 2018

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Co-localisation of non-cartilaginous articular pathology increases risk of cartilage loss in the tibiofemoral joint--the MOST study

21 January 2018

1 reference

Prevalent cartilage damage and cartilage loss over time are associated with incident bone marrow lesions in the tibiofemoral compartments: the MOST study.

21 January 2018

1 reference

Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults

21 January 2018

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Osteoimmunology in rheumatic diseases

21 January 2018

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Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis.

21 January 2018

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21 January 2018

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Osteochondral alterations in osteoarthritis

21 January 2018

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Targeting subchondral bone for treating osteoarthritis: what is the evidence?

21 January 2018

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Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture

21 January 2018

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Tartrate-resistant acid phosphatase as an immunohistochemical marker for inflammatory macrophages.

21 January 2018

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Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

21 January 2018

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Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo

21 January 2018

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Cord blood-derived macrophage-lineage cells rapidly stimulate osteoblastic maturation in mesenchymal stem cells in a glycoprotein-130 dependent manner

21 January 2018

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Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling

21 January 2018

1 reference

Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis

21 January 2018

1 reference

Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts

21 January 2018

1 reference

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

21 January 2018

1 reference

Intra-articular clodronate for the treatment of knee osteoarthritis: dose ranging study vs hyaluronic acid.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JOR.23009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26250062%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference