Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo. (Q52011176)

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11 November 2019

title

Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo (English)

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11 November 2019

2

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11 November 2019

Masashi J Rotte

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11 November 2019

author name string

Chang-You Wu

1

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11 November 2019

Dylan F Davey

4

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11 November 2019

Steve P Perfetto

5

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11 November 2019

Elizabeth G Rhee

6

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11 November 2019

Brenda L Freidag

7

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11 November 2019

Brenna J Hill

8

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11 November 2019

Daniel C Douek

9

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11 November 2019

Robert A Seder

10

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11 November 2019

language of work or name

English

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publication date

12 August 2002

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11 November 2019

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11 November 2019

volume

3

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issue

9

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11 November 2019

page(s)

852-858

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Functional diversity of helper T lymphocytes

11 November 2019

cites work

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7 January 2021

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IL-12 is required to maintain a Th1 response during Leishmania major infection.

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Cutting edge: IL-12 is required for the maintenance of IFN-gamma production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii

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Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

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Persistence of pathogenic CD4+ Th1-like cells in vivo in the absence of IL-12 but in the presence of autoantigen.

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Differentiated Th1 autoreactive effector cells can induce experimental autoimmune encephalomyelitis in the absence of IL-12 and CD40/CD40L interactions

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In differentiated CD4+ T cells, interleukin 4 production is cytokine-autonomous, whereas interferon gamma production is cytokine-dependent

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Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen

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Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations

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Withdrawal of stimulation may initiate the transition of effector to memory CD4 cells

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Heterogeneity of the memory CD4 T cell response: persisting effectors and resting memory T cells.

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Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

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Migration and function of antigen-primed nonpolarized T lymphocytes in vivo

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CD4(+) T cell effectors can become memory cells with high efficiency and without further division.

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7 January 2021

Visualizing the generation of memory CD4 T cells in the whole body

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7 January 2021

Preferential localization of effector memory cells in nonlymphoid tissue

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7 January 2021

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

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7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

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7 January 2021

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

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7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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7 January 2021

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

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7 January 2021

Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis

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7 January 2021

Linear differentiation of cytotoxic effectors into memory T lymphocytes

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7 January 2021

Modelling T-cell memory by genetic marking of memory T cells in vivo

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7 January 2021

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

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7 January 2021

Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation

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7 January 2021

Helper T cell differentiation is controlled by the cell cycle

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7 January 2021

Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression

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7 January 2021

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

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7 January 2021

In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells

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7 January 2021

Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses

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7 January 2021

Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells

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7 January 2021

Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection

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7 January 2021

Virus-specific CD8+ T-cell memory determined by clonal burst size

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7 January 2021

Immunogenicity and protective efficacy of a tuberculosis DNA vaccine

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7 January 2021

Vaccination with heat-killed leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against leishmania major infection

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7 January 2021

A new mathematical model for relative quantification in real-time RT-PCR

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7 January 2021

Identifiers

DOI

10.1038/NI832

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11 November 2019

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