p53 activity is essential for normal development in Xenopus. (Q52192096)

26 April 2018

title

p53 activity is essential for normal development in Xenopus. (English)

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26 April 2018

author name string

J B Wallingford

1

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26 April 2018

D W Seufert

2

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26 April 2018

V C Virta

3

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26 April 2018

P D Vize

4

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26 April 2018

language of work or name

English

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publication date

1 October 1997

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26 April 2018

published in

Current Biology

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26 April 2018

volume

7

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26 April 2018

issue

10

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26 April 2018

page(s)

747-757

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26 April 2018

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

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The p53 proto-oncogene can act as a suppressor of transformation

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A subset of p53-deficient embryos exhibit exencephaly

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Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

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A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

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p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells

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Tumor suppressors: a developing role for p53?

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7 January 2021

Stabilization and expression of high levels of p53 during early development in Xenopus laevis.

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A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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AP-1/jun is required for early Xenopus development and mediates mesoderm induction by fibroblast growth factor but not by activin

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Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

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Mutations in the p53 gene occur in diverse human tumour types

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Dosage-dependent dominance over wild-type p53 of a mutant p53 isolated from nasopharyngeal carcinoma.

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7 January 2021

Chapter 20 Assays for Gene Function in Developing Xenopus Embryos

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7 January 2021

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

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7 January 2021

Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis

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Involvement of p21ras in Xenopus mesoderm induction

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7 January 2021

Induction of mesoderm by a viral oncogene in early Xenopus embryos.

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7 January 2021

In vivo regulation of the early embryonic cell cycle in Xenopus

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7 January 2021

Growth cone interactions with a glial cell line from embryonic Xenopus retina

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7 January 2021

Monoclonal antibodies identify blastemal cells derived from dedifferentiating muscle in newt limb regeneration

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7 January 2021

Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys

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7 January 2021

Physical and functional interaction between WT1 and p53 proteins

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7 January 2021

Development of the Xenopus pronephric system

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7 January 2021

Regulation of the Cellular p53 Tumor Antigen in Teratocarcinoma Cells and Their Differentiated Progeny

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7 January 2021

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7 January 2021

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

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7 January 2021

A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription

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7 January 2021

The mRNA encoding elongation factor 1-alpha (EF-1 alpha) is a major transcript at the midblastula transition in Xenopus

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7 January 2021

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

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7 January 2021

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

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7 January 2021

Identification of a developmental timer regulating the stability of embryonic cyclin A and a new somatic A-type cyclin at gastrulation.

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7 January 2021

Regulation of the specific DNA binding function of p53

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7 January 2021

A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

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7 January 2021

MyoD or Myf-5 is required for the formation of skeletal muscle

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7 January 2021

Functional analysis of activins during mammalian development.

1 reference

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7 January 2021

Different phenotypes for mice deficient in either activins or activin receptor type II

1 reference

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7 January 2021

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1 reference

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7 January 2021

10.1016/S0960-9822(06)00333-2

Identifiers

DOI

1 reference

26 April 2018

release_n6enlq6k4bgi5anqiz6odm4v3i

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/n6enlq6k4bgi5anqiz6odm4v3i

24 November 2022

mapped directly with Wikidata item

PubMed ID

9368757

1 reference

26 April 2018