Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. (Q52348575)

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20 March 2020

meta-analysis

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title

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis (English)

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20 March 2020

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8

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Eleftheria Zeggini

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Konstantinos Hatzikotoulas

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Julia Steinberg

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Fernando P Hartwig

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Loz Southam

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Unnur Styrkarsdottir

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Daniel Suveges

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Helgi Jonsson

14

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Andrew W McCaskie

16

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George Davey Smith

21

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Jeremy Mark Wilkinson

22

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18

Joyce B J van Meurs

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20 March 2020

author name string

Eleni Zengini

1

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Ioanna Tachmazidou

3

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Sophie Hackinger

7

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Arthur Gilly

10

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Britt Killian

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Thorvaldur Ingvarsson

13

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George C Babis

15

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Andre G Uitterlinden

17

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Unnur Thorsteinsdottir

19

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Kari Stefansson

20

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language of work or name

English

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publication date

20 March 2018

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volume

50

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issue

4

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20 March 2020

page(s)

549-558

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describes a project that uses

20 March 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5896734

inferred from PubMed Central ID database lookup

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7 September 2018

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7 September 2018

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7 September 2018

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7 September 2018

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7 September 2018

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Rho/ROCK and MEK/ERK activation by transforming growth factor-alpha induces articular cartilage degradation

7 September 2018

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7 September 2018

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A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration

7 September 2018

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Large-scale proteomics and phosphoproteomics of urinary exosomes

7 September 2018

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Reduced limb length and worsened osteoarthritis in adult mice after genetic inhibition of p38 MAP kinase activity in cartilage

7 September 2018

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CHECK (Cohort Hip and Cohort Knee): similarities and differences with the Osteoarthritis Initiative

7 September 2018

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Comparison between osteoblasts derived from human dental pulp stem cells and osteosarcoma cell lines

7 September 2018

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Oxidative stress reaction in the meniscus of Bach 1 deficient mice: potential prevention of meniscal degeneration

7 September 2018

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7 September 2018

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A new multipoint method for genome-wide association studies by imputation of genotypes

7 September 2018

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A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis

7 September 2018

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7 September 2018

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‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

7 September 2018

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7 September 2018

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7 September 2018

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Transforming growth factor alpha suppression of articular chondrocyte phenotype and Sox9 expression in a rat model of osteoarthritis

7 September 2018

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7 January 2021

GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes

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An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage

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7 January 2021

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29559693%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29559693%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

29559693

1 reference