Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in somatostatin-induced apoptosis. (Q52538529)

2 May 2018

title

Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in somatostatin-induced apoptosis. (English)

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2 May 2018

author name string

Liu D

1

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2 May 2018

Martino G

2

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2 May 2018

Thangaraju M

3

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2 May 2018

Sharma M

4

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2 May 2018

Halwani F

5

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2 May 2018

Shen SH

6

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2 May 2018

Patel YC

7

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2 May 2018

Srikant CB

8

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2 May 2018

language of work or name

English

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publication date

1 March 2000

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2 May 2018

Journal of Biological Chemistry

published in

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2 May 2018

volume

275

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2 May 2018

issue

13

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2 May 2018

page(s)

9244-9250

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2 May 2018

Caspases: the executioners of apoptosis

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Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

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Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

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Mitochondrial permeability transition is a central coordinating event of apoptosis

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The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes.

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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Different modes of cell death induced by 5-fluoro-2'-deoxyuridine in two clones of the mouse mammary tumor FM3A cell line

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Intracellular acidification during apoptosis can occur in the absence of a nucleus

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Induction of wild-type p53, Bax, and acidic endonuclease during somatostatin-signaled apoptosis in MCF-7 human breast cancer cells

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

21 January 2018

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Induction of apoptosis by valinomycin: mitochondrial permeability transition causes intracellular acidification

21 January 2018

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Na+/H+ exchangers of mammalian cells.

21 January 2018

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Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

21 January 2018

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FLICE Induced Apoptosis in a Cell-free System

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.275.13.9244

1 reference

2 May 2018

PubMed ID

10734062

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2 May 2018