Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Trial. (Q52599940)

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scientific article published on 7 April 2018

Language	Label	Description	Also known as
English	Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Trial.	scientific article published on 7 April 2018

Statements

scholarly article

1 reference

Europe PubMed Central

29 June 2018

http://europepmc.org/abstract/PMC/6005227

Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Trial. (English)

1 reference

Europe PubMed Central

29 June 2018

http://europepmc.org/abstract/PMC/6005227

1 reference

based on heuristic

inferred from title

multicenter clinical trial

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

1

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Shizuya Yamashita

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Koutaro Yokote

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Eiichi Araki

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Hideki Suganami

5

1 reference

Europe PubMed Central

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9 June 2020

Shun Ishibashi

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

K-877 Study Group

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

7 April 2018

1 reference

Europe PubMed Central

29 June 2018

http://europepmc.org/abstract/PMC/6005227

Journal of Atherosclerosis and Thrombosis

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

25

1 reference

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9 June 2020

521-538

1 reference

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9 June 2020

6

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Efficacy and safety of pemafibrate (K-877), a selective peroxisome proliferator-activated receptor α modulator, in patients with dyslipidemia: Results from a 24-week, randomized, double blind, active-controlled, phase 3 trial.

1 reference

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30 June 2018

Pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor alpha modulator for management of atherogenic dyslipidaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

30 June 2018

Efficacy and safety of K-877, a novel selective peroxisome proliferator-activated receptor α modulator (SPPARMα), in combination with statin treatment: Two randomised, double-blind, placebo-controlled clinical trials in patients with dyslipidaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

30 June 2018

PPAR-α agonists are still on the rise: an update on clinical and experimental findings

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30 June 2018

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

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30 June 2018

Postprandial Hyperlipidemia and Remnant Lipoproteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

30 June 2018

Fibrates for secondary prevention of cardiovascular disease and stroke

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30 June 2018

Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials

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30 June 2018

Selective peroxisome proliferator-activated receptor α modulators (SPPARMα): the next generation of peroxisome proliferator-activated receptor α-agonists

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30 June 2018

KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update

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30 June 2018

Fibrates effect on cardiovascular risk is greater in patients with high triglyceride levels or atherogenic dyslipidemia profile: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

30 June 2018

Effects of combination lipid therapy in type 2 diabetes mellitus

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30 June 2018

Fenofibrate: treatment of hyperlipidemia and beyond

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

30 June 2018

Safety considerations with fibrate therapy

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30 June 2018

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

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30 June 2018

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report

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30 June 2018

Mechanism of action of fibrates on lipid and lipoprotein metabolism

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30 June 2018

Identification and Characterization of Fenofibrate-Induced Liver Injury.

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13 August 2018

Pemafibrate: First Global Approval.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

13 August 2018

A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

13 August 2018

Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6005227

13 August 2018

Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver.

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13 August 2018

Effects of fenofibric acid on carotid intima-media thickness in patients with mixed dyslipidemia on atorvastatin therapy: randomized, placebo-controlled study (FIRST).

1 reference

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13 August 2018

Prevention of cardiovascular disease utilizing fibrates--a pooled meta-analysis

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13 August 2018

Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor α agonists

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30 November 2018

Identifiers

10.5551/JAT.44412

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29628483%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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