The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. (Q52661639)

5 May 2018

title

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. (English)

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5 May 2018

author name string

Jinbo Han

1

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5 May 2018

Erwei Li

2

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5 May 2018

Liqun Chen

3

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5 May 2018

Yuanyuan Zhang

4

1 reference

5 May 2018

Fangchao Wei

5

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5 May 2018

Jieyuan Liu

6

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5 May 2018

Haiteng Deng

7

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5 May 2018

Yiguo Wang

8

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5 May 2018

language of work or name

English

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publication date

6 July 2015

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5 May 2018

published in

Nature

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5 May 2018

volume

524

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5 May 2018

issue

7564

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5 May 2018

page(s)

243-246

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5 May 2018

Mechanisms for insulin resistance: common threads and missing links

cites work

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Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles

21 January 2018

1 reference

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Protein sensors for membrane sterols

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

21 January 2018

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CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

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A Central role for mTOR in lipid homeostasis

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COPII and the regulation of protein sorting in mammals

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Selective versus total insulin resistance: a pathogenic paradox

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Hormonal regulation of hepatic glucose production in health and disease

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Genetic control of de novo lipogenesis: role in diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14557

Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14557

CRTC3 links catecholamine signalling to energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14557

The Creb1 coactivator Crtc1 is required for energy balance and fertility

21 January 2018

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Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes

21 January 2018

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Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31

21 January 2018

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mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

21 January 2018

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Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

21 January 2018

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SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

21 January 2018

1 reference

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Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

21 January 2018

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The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

21 January 2018

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Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

21 January 2018

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

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Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1

21 January 2018

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Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity

21 January 2018

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Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

21 January 2018

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In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles

21 January 2018

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Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26147081

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26147081

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE14557

1 reference

5 May 2018

Dimensions Publication ID

1016552151

0 references

1 reference

5 May 2018