The Alzheimer's disease related tau protein as a new target for chemical protein engineering. (Q52890311)

9 May 2018

title

The Alzheimer's disease related tau protein as a new target for chemical protein engineering. (English)

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9 May 2018

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3

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Christian Hackenberger

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4

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9 May 2018

author name string

Malgorzata Broncel

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1

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9 May 2018

Eberhard Krause

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2

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9 May 2018

language of work or name

English

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publication date

9 January 2012

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9 May 2018

Chemistry—A European Journal

published in

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9 May 2018

volume

18

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issue

9

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9 May 2018

page(s)

2488-2492

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9 May 2018

A protein factor essential for microtubule assembly

cites work

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201103032

Dysregulation of protein phosphorylation/dephosphorylation in Alzheimer's disease: a therapeutic target

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Post-translational modifications of tau protein in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Charge-pairing mechanism of phosphorylation effect upon amyloid fibrillation of human tau core peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201103032

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201103032

Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201103032

NMR analysis of a Tau phosphorylation pattern

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Rapid purification of truncated tau proteins: model approach to purification of functionally active fragments of disordered proteins, implication for neurodegenerative diseases.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Expressed protein ligation: a general method for protein engineering

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3beta

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Synthesis of proteins by native chemical ligation

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Chemoselective ligation and modification strategies for peptides and proteins.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Semisynthesis of proteins by expressed protein ligation

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Crystal Structure of a Phosphorylated Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201103032

Photocontrol of Smad2, a multiphosphorylated cell-signaling protein, through caging of activating phosphoserines

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Intein-mediated biotinylation of proteins and its application in a protein microarray

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Protein synthesis by native chemical ligation: expanded scope by using straightforward methodology

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

Spectroscopic studies of GSK3{beta} phosphorylation of the neuronal tau protein and its interaction with the N-terminal domain of apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201103032

The self-assembly ability of the first microtubule-binding repeat from tau and its modulation by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201103032

21 January 2018

Identifiers

DOI

10.1002/CHEM.201103032

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9 May 2018

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9 May 2018