piRNA-823 contributes to tumorigenesis by regulating de novo DNA methylation and angiogenesis in multiple myeloma. (Q53239319)

12 May 2018

title

piRNA-823 contributes to tumorigenesis by regulating de novo DNA methylation and angiogenesis in multiple myeloma. (English)

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12 May 2018

0 references

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H Yan

1

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12 May 2018

Q-L Wu

2

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C-Y Sun

3

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12 May 2018

L-S Ai

4

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J Deng

5

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L Zhang

6

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L Chen

7

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Z-B Chu

8

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B Tang

9

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K Wang

10

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X-F Wu

11

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J Xu

12

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Y Hu

13

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publication date

15 April 2014

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12 May 2018

published in

Leukemia

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12 May 2018

volume

29

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12 May 2018

issue

1

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12 May 2018

page(s)

196-206

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The genetic architecture of multiple myeloma.

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1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.135

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Aberrant gene methylation implicated in the progression of monoclonal gammopathy of undetermined significance to multiple myeloma

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The fundamental role of epigenetic events in cancer

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Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.

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Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.

21 January 2018

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DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

21 January 2018

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Non-coding RNAs in human disease

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Epigenetic inactivation of the MIR34B/C in multiple myeloma.

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Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development

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Epigenetic inactivation of the miR-34a in hematological malignancies

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A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice

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Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.

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A novel class of small RNAs in mouse spermatogenic cells

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DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

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Developmentally regulated piRNA clusters implicate MILI in transposon control

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Hiwi mediated tumorigenesis is associated with DNA hypermethylation

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Piwis and piwi-interacting RNAs in the epigenetics of cancer

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Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila.

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piRNA, the new non-coding RNA, is aberrantly expressed in human cancer cells.

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piR-823, a novel non-coding small RNA, demonstrates in vitro and in vivo tumor suppressive activity in human gastric cancer cells

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Identification of brain-derived neurotrophic factor as a novel angiogenic protein in multiple myeloma

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Altered expression of piRNAs and their relation with clinicopathologic features of breast cancer

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Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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https://api.crossref.org/works/10.1038%2FLEU.2014.135

Syndecan-1 promotes the angiogenic phenotype of multiple myeloma endothelial cells.

21 January 2018

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Gene hypermethylation in multiple myeloma: lessons from a cancer pathway approach.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2014.135

Concurrent p16 methylation pattern as an adverse prognostic factor in multiple myeloma: a methylation-specific polymerase chain reaction study using two different primer sets.

21 January 2018

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The expression of stem cell protein Piwil2 and piR-932 in breast cancer.

21 January 2018

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International staging system for multiple myeloma

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Improved risk stratification in myeloma using a microRNA-based classifier.

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MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

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Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis

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The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2014.135

Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3/Bcl-XL pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2014.135

Pathways of proliferation and antiapoptosis driven in breast cancer stem cells by stem cell protein piwil2.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2014.135

Disruption of INK4/CDK/Rb cell cycle pathway by gene hypermethylation in multiple myeloma and MGUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.135

Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.135

Angiostatic activity of DNA methyltransferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.135

Loss of p16INK4a expression is associated with vascular endothelial growth factor expression in squamous cell carcinoma of the esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.135

Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.135

A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma

21 January 2018

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12 December 2020

Detection of circulating tumor cells in peripheral blood from patients with gastric cancer using piRNAs as markers

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12 December 2020

Worms gang up on bacteria

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12 December 2020

Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus

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12 December 2020

The PIWI protein acts as a predictive marker for human gastric cancer

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12 December 2020

Bone marrow angiogenesis in patients with active multiple myeloma.

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12 December 2020

Infrequent epigenetic dysregulation of CIP/KIP family of cyclin-dependent kinase inhibitors in multiple myeloma

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12 December 2020

A VEGF-dependent autocrine loop mediates proliferation and capillarogenesis in bone marrow endothelial cells of patients with multiple myeloma.

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12 December 2020

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

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12 December 2020

A novel class of small RNAs bind to MILI protein in mouse testes

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12 December 2020

Alterations of the cyclin D1/pRb/p16(INK4A) pathway in multiple myeloma

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12 December 2020

DNA methylation changes in multiple myeloma

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12 December 2020

Prognostic value of bone marrow angiogenesis in multiple myeloma

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12 December 2020

RB2/p130 gene-enhanced expression down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in vivo

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12 December 2020

A germline-specific class of small RNAs binds mammalian Piwi proteins

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12 December 2020

Identifiers

DOI

10.1038/LEU.2014.135

1 reference

12 May 2018

1 reference

12 May 2018