ILSI-HESI cardiovascular safety subcommittee initiative: evaluation of three non-clinical models of QT prolongation. (Q53252784)

12 May 2018

title

ILSI-HESI cardiovascular safety subcommittee initiative: evaluation of three non-clinical models of QT prolongation. (English)

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12 May 2018

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Laurie A Hanson

1

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12 May 2018

Alan S Bass

2

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12 May 2018

Gary Gintant

3

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12 May 2018

Scott Mittelstadt

4

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12 May 2018

David Rampe

5

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12 May 2018

Karluss Thomas

6

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12 May 2018

publication date

9 May 2006

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12 May 2018

Journal of Pharmacological and Toxicological Methods

published in

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12 May 2018

volume

54

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12 May 2018

issue

2

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12 May 2018

page(s)

116-129

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12 May 2018

A method for QT correction based on beat-to-beat analysis of the QT/RR interval relationship in conscious telemetred beagle dogs

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Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic

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Blinded test in isolated female rabbit heart reliably identifies action potential duration prolongation and proarrhythmic drugs: importance of triangulation, reverse use dependence, and instability

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7 January 2021

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7 January 2021

Identifiers

DOI

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12 May 2018

PubMed ID

16843688

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12 May 2018