Proinsulin C-peptide prevents impaired wound healing by activating angiogenesis in diabetes. (Q53270986)

12 May 2018

title

Proinsulin C-peptide prevents impaired wound healing by activating angiogenesis in diabetes. (English)

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12 May 2018

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Young-Cheol Lim

1

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12 May 2018

Mahendra Prasad Bhatt

2

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12 May 2018

Mi-Hye Kwon

3

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12 May 2018

Donghyun Park

4

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12 May 2018

SungHun Na

5

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12 May 2018

Young-Myeong Kim

6

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12 May 2018

Kwon-Soo Ha

7

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12 May 2018

language of work or name

English

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publication date

9 July 2014

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12 May 2018

Journal of Investigative Dermatology

published in

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12 May 2018

volume

135

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12 May 2018

issue

1

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12 May 2018

page(s)

269-278

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/jid.2014.285

exact match

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cites work

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C-peptide prevents hyperglycemia-induced endothelial apoptosis through inhibition of reactive oxygen species-mediated transglutaminase 2 activation

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C-peptide activates AMPKα and prevents ROS-mediated mitochondrial fission and endothelial apoptosis in diabetes

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The redox enzyme p66Shc contributes to diabetes and ischemia-induced delay in cutaneous wound healing.

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HoxD3 accelerates wound healing in diabetic mice

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C-peptide as a therapeutic tool in diabetic nephropathy.

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Proinsulin C-peptide activates cAMP response element-binding proteins through the p38 mitogen-activated protein kinase pathway in mouse lung capillary endothelial cells

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Prevention of VEGF-mediated microvascular permeability by C-peptide in diabetic mice.

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C-peptide is a bioactive peptide

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The clinical potential of C-peptide replacement in type 1 diabetes

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7 January 2021

Stimulation of endothelial nitric oxide synthase by proinsulin C-peptide

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7 January 2021

Regulation of wound healing by growth factors and cytokines

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Abnormal cell responses and role of TNF-α in impaired diabetic wound healing

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Different roles of ERK and p38 MAP kinases during tube formation from endothelial cells cultured in 3-dimensional collagen matrices

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C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells

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7 January 2021

Identifiers

DOI

10.1038/JID.2014.285

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12 May 2018

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12 May 2018