IL-15 exacerbates collagen-induced arthritis with an enhanced CD4+ T cell response to produce IL-17. (Q53529589)

15 May 2018

title

IL-15 exacerbates collagen-induced arthritis with an enhanced CD4+ T cell response to produce IL-17. (English)

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15 May 2018

author name string

Kazufumi Yoshihara

1

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15 May 2018

Hisakata Yamada

2

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15 May 2018

Akiko Hori

3

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15 May 2018

Toshiki Yajima

4

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15 May 2018

Chiharu Kubo

5

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15 May 2018

Yasunobu Yoshikai

6

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15 May 2018

language of work or name

English

0 references

publication date

1 October 2007

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15 May 2018

European Journal of Immunology

published in

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15 May 2018

volume

37

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15 May 2018

issue

10

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15 May 2018

page(s)

2744-2752

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15 May 2018

Microbial lipopeptides induce the production of IL-17 in Th cells.

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Targeting IL-15 receptor-bearing cells with an antagonist mutant IL-15/Fc protein prevents disease development and progression in murine collagen-induced arthritis.

21 January 2018

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IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.

21 January 2018

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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

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IL-15 regulates CD8+ T cell contraction during primary infection.

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Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein

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Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist.

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The molecular pathogenesis of collagen-induced arthritis in mice--a model for rheumatoid arthritis

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Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis

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7 January 2021

Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee

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7 January 2021

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

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7 January 2021

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

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7 January 2021

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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7 January 2021

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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7 January 2021

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

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7 January 2021

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

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IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels

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7 January 2021

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

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Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor

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7 January 2021

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

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7 January 2021

Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo

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Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis

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7 January 2021

Fibroblast-like synoviocytes from rheumatoid arthritis patients express functional IL-15 receptor complex: endogenous IL-15 in autocrine fashion enhances cell proliferation and expression of Bcl-x(L) and Bcl-2

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7 January 2021

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

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7 January 2021

Increased expression of IL-15 in the synovium of patients with rheumatoid arthritis compared with patients with Yersinia-induced arthritis and osteoarthritis

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7 January 2021

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

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7 January 2021

Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study

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7 January 2021

High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism

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7 January 2021

Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritis

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7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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7 January 2021

Transforming growth factor-beta induces development of the T(H)17 lineage

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7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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7 January 2021

A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits

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7 January 2021

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

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7 January 2021

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

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7 January 2021

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

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7 January 2021

Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling

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7 January 2021

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

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7 January 2021

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

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7 January 2021

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

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7 January 2021

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

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7 January 2021

Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo

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7 January 2021

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis

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7 January 2021

Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia

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7 January 2021

Identifiers

DOI

10.1002/EJI.200737229

1 reference

15 May 2018

release_siukmizb2zdidiptqpb5t6srme

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/siukmizb2zdidiptqpb5t6srme

24 November 2022

mapped directly with Wikidata item

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15 May 2018