Mitotic activation of Akt signalling pathway in Han:SPRD rats with polycystic kidney disease. (Q53540395)

15 May 2018

title

Mitotic activation of Akt signalling pathway in Han:SPRD rats with polycystic kidney disease. (English)

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15 May 2018

author name string

Patricia R Wahl

1

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15 May 2018

Michel Le Hir

2

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Alexander Vogetseder

3

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Alexandre Arcaro

4

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Astrid Starke

5

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Ying Waeckerle-Men

6

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Andreas L Serra

7

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Rudolf P Wuthrich

8

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publication date

1 August 2007

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15 May 2018

published in

Nephrology

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15 May 2018

volume

12

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issue

4

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page(s)

357-363

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15 May 2018

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

cites work

1 reference

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

Evaluation of two phosphorylation sites improves the prognostic significance of Akt activation in non-small-cell lung cancer tumors

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

Requirement for phosphatidylinositol-3 kinase activity during progression through S-phase and entry into mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1797.2007.00811.X

10.1111/J.1440-1797.2007.00811.X

21 January 2018

Identifiers

DOI

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15 May 2018

PubMed ID

17635750

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15 May 2018