Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site. (Q53548163)

15 May 2018

title

Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site. (English)

1 reference

15 May 2018

1 reference

4

1 reference

15 May 2018

author name string

Andrew J Gale

1

1 reference

15 May 2018

Subramanian Yegneswaran

2

1 reference

15 May 2018

Xiao Xu

3

1 reference

15 May 2018

John H Griffin

5

1 reference

15 May 2018

language of work or name

English

0 references

publication date

6 June 2007

1 reference

15 May 2018

Journal of Biological Chemistry

number of pages

8

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

15 May 2018

volume

282

1 reference

15 May 2018

issue

30

1 reference

15 May 2018

page(s)

21848-21855

1 reference

15 May 2018

The dynamics of thrombin formation

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Proteases in blood clotting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Complete cDNA and derived amino acid sequence of human factor V

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Proposed structural models of the prothrombinase (FXa-FVa) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Binding site for blood coagulation factor Xa involving residues 311-325 in factor Va.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Binding sites for blood coagulation factor Xa and protein S involving residues 493-506 in factor Va.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Amino Acids Glu323, Tyr324, Glu330, and Val331 of Factor Va Heavy Chain Are Essential for Expression of Cofactor Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

The sequence Glu1811-Lys1818 of human blood coagulation factor VIII comprises a binding site for activated factor IX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Mutating factor VIII: lessons from structure to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Mutations associated with hemophilia A in the 558-565 loop of the factor VIIIa A2 subunit alter the catalytic activity of the factor Xase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Peptide Bond Cleavages and Loss of Functional Activity during Inactivation of Factor Va and Factor VaR506Q by Activated Protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Role of P1 residues Arg336 and Arg562 in the activated-Protein-C-catalysed inactivation of Factor VIIIa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Importance of individual activated protein C cleavage site regions in coagulation factor V for factor Va inactivation and for factor Xa activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Intrinsic stability and functional properties of disulfide bond-stabilized coagulation factor VIIIa variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Prothrombin residues 473-487 contribute to factor Va binding in the prothrombinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Identification of distinct sequences in human blood coagulation factor Xa and prothrombin essential for substrate and cofactor recognition in the prothrombinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Identification of functionally important residues in proteins using comparative models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Defining the factor Xa-binding site on factor Va by site-directed glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

A control switch for prothrombinase: characterization of a hirudin-like pentapeptide from the COOH terminus of factor Va heavy chain that regulates the rate and pathway for prothrombin activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Analysis of the kinetics of prothrombin activation and evidence that two equilibrating forms of prothrombinase are involved in the process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Binding of substrate in two conformations to human prothrombinase drives consecutive cleavage at two sites in prothrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

Soluble Phospholipids Enhance Factor Xa-Catalyzed Prothrombin Activation in Solution†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702192200

21 January 2018

Identifiers

DOI

10.1074/JBC.M702192200

1 reference

15 May 2018

1 reference

15 May 2018