Growth suppression of human mast cells expressing constitutively active c-kit receptors by JNK inhibitor SP600125. (Q53604077)

16 May 2018

title

Growth suppression of human mast cells expressing constitutively active c-kit receptors by JNK inhibitor SP600125. (English)

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16 May 2018

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Bin Wang

1

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16 May 2018

Junichi Tsukada

2

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16 May 2018

Takehiro Higashi

3

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16 May 2018

Takamitsu Mizobe

4

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16 May 2018

Ai Matsuura

5

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Fumihiko Mouri

6

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16 May 2018

Norifumi Sawamukai

7

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16 May 2018

Chisei Ra

8

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Yoshiya Tanaka

9

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publication date

1 September 2006

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16 May 2018

published in

Genes to Cells

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volume

11

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16 May 2018

issue

9

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page(s)

983-992

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The biology of Kit in disease and the application of pharmacogenetics

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

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21 January 2018

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The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations

21 January 2018

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Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

21 January 2018

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Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-Kit-mediated cytokine-independent survival and proliferation in human leukemia cells

21 January 2018

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

21 January 2018

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Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene

21 January 2018

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A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors

21 January 2018

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H-Ras/mitogen-activated protein kinase pathway inhibits integrin-mediated adhesion and induces apoptosis in osteoblasts

21 January 2018

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Activating c-kit gene mutations in human germ cell tumors

21 January 2018

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Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

21 January 2018

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

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A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria

21 January 2018

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c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

21 January 2018

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Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms

21 January 2018

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21 January 2018

Identifiers

DOI

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16 May 2018

1 reference

16 May 2018